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    Neurog3 neurogenin 3 [ Mus musculus (house mouse) ]

    Gene ID: 11925, updated on 11-Jul-2017
    Official Symbol
    Neurog3provided by MGI
    Official Full Name
    neurogenin 3provided by MGI
    Primary source
    MGI:MGI:893591
    See related
    Ensembl:ENSMUSG00000044312
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ngn3; Atoh5; Math4B; bHLHa7
    Orthologs
    Location:
    10; 10 B4
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (62133090..62134763)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (61595838..61597511)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene argininosuccinate synthase pseudogene Neighboring gene RIKEN cDNA 2010107G23 gene Neighboring gene tetraspanin 15 Neighboring gene microRNA 7662 Neighboring gene tachykinin receptor 2

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC129292, MGC129293

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    endocrine pancreas development IEA
    Inferred from Electronic Annotation
    more info
     
    epithelial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    neurogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of sequence-specific DNA binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of dendrite morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transdifferentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    neurogenin-3
    Names
    NGN-3
    Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B)
    atonal homolog 5
    helix-loop-helix protein mATH-4B
    protein atonal homolog 5

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009719.6NP_033849.3  neurogenin-3

      See identical proteins and their annotated locations for NP_033849.3

      Status: VALIDATED

      Source sequence(s)
      AC127417
      Consensus CDS
      CCDS23887.1
      UniProtKB/Swiss-Prot
      P70661
      UniProtKB/TrEMBL
      Q548G3
      Related
      ENSMUSP00000054054.1, ENSMUST00000050103.1
      Conserved Domains (1) summary
      cd00083
      Location:81140
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      62133090..62134763
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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