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    acr-2 Acetylcholine receptor subunit beta-type acr-2 [ Caenorhabditis elegans ]

    Gene ID: 180936, updated on 27-Mar-2017
    Gene symbol
    acr-2
    Gene description
    Acetylcholine receptor subunit beta-type acr-2
    Primary source
    WormBase:WBGene00000042
    Locus tag
    CELE_K11G12.2
    Gene type
    protein coding
    RNA name
    Acetylcholine receptor subunit beta-type acr-2
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See acr-2 in Map Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (6702692..6709142)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Acetylcholine receptor subunit beta-type acr-3 Neighboring gene Zinc metalloproteinase nas-11

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    contributes_to acetylcholine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to acetylcholine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to acetylcholine-gated cation-selective channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to excitatory extracellular ligand-gated ion channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular ligand-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    calcium ion import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    excitatory postsynaptic potential IEA
    Inferred from Electronic Annotation
    more info
     
    inorganic cation transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    neuromuscular synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
     
    response to nicotine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic transmission, GABAergic IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    synaptic transmission, cholinergic IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    synaptic transmission, cholinergic IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    acetylcholine-gated channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Acetylcholine receptor subunit beta-type acr-2
    NP_509128.1
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6702692..6709142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076727.5NP_509128.1  Acetylcholine receptor subunit beta-type acr-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509128.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48182
      Conserved Domains (3) summary
      TIGR00860
      Location:54544
      LIC; Cation transporter family protein
      pfam02931
      Location:60265
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:272544
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
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