Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Fscn2 fascin actin-bundling protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 238021, updated on 22-Aug-2017
    Official Symbol
    Fscn2provided by MGI
    Official Full Name
    fascin actin-bundling protein 2provided by MGI
    Primary source
    MGI:MGI:2443337
    See related
    Ensembl:ENSMUSG00000025380 Vega:OTTMUSG00000004147
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ahl8; A930022G03; C630046B20Rik
    Orthologs
    Location:
    11; 11 E2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (120358366..120368173)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (120222848..120229487)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 0610009L18 gene Neighboring gene microRNA 6935 Neighboring gene actin, gamma, cytoplasmic 1 Neighboring gene Fanconi anemia core complex associated protein 100 Neighboring gene NPL4 homolog, ubiquitin recognition factor

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Clone Names

    • MGC130378, MGC130379

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein binding, bridging IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament bundle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    actin filament organization IEA
    Inferred from Electronic Annotation
    more info
     
    cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    establishment or maintenance of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    eye photoreceptor cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    filamentous actin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    stereocilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    fascin-2
    Names
    fascin homolog 2, actin-bundling protein, retinal
    retinal fascin

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172802.4NP_766390.2  fascin-2

      See identical proteins and their annotated locations for NP_766390.2

      Status: VALIDATED

      Source sequence(s)
      AK050002, BB279997, BC109356
      Consensus CDS
      CCDS25731.1
      UniProtKB/Swiss-Prot
      Q32M02
      Related
      ENSMUSP00000026445.2, OTTMUSP00000004566, ENSMUST00000026445.2, OTTMUST00000009385
      Conserved Domains (2) summary
      cd00257
      Location:381492
      Fascin; Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an ...
      pfam06268
      Location:266376
      Fascin; Fascin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      120358366..120368173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533259.3XP_006533322.1  fascin-2 isoform X1

      Conserved Domains (2) summary
      cd00257
      Location:408519
      Fascin; Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an ...
      pfam06268
      Location:266373
      Fascin; Fascin domain
    Support Center