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    Fgf9 fibroblast growth factor 9 [ Mus musculus (house mouse) ]

    Gene ID: 14180, updated on 12-Mar-2017
    Official Symbol
    Fgf9provided by MGI
    Official Full Name
    fibroblast growth factor 9provided by MGI
    Primary source
    MGI:MGI:104723
    See related
    Ensembl:ENSMUSG00000021974 Vega:OTTMUSG00000036883
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Eks
    Orthologs
    Location:
    14 C3; 14 30.51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (58072686..58112854)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (58691523..58731557)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene mitochondrial calcium uptake 2 Neighboring gene RIKEN cDNA 3110083C13 gene Neighboring gene high mobility group box 3 pseudogene Neighboring gene ribosomal protein S8 pseudogene Neighboring gene predicted gene, 33321

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    fibroblast growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    growth factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    heparin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    angiogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cardiac left ventricle morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    cardiac ventricle development TAS
    Traceable Author Statement
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cell-cell signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chondrocyte differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    chondrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic digestive tract development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic limb morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic skeletal system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    eye development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fibroblast growth factor receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    fibroblast growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fibroblast growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    inner ear morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lung development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lung development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lung-associated mesenchyme development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male sex determination IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    male sex determination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of Wnt signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    osteoblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of activin receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of canonical Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cardiac muscle cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of cardiac muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cardiac muscle cell proliferation TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of cell division IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of mesenchymal cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of mesenchymal cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of smoothened signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of smoothened signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of vascular endothelial growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of timing of cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vasculogenesis involved in coronary vascular morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    basement membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    fibroblast growth factor 9
    Names
    FGF-9
    GAF
    HBGF-9
    elbow knee synostosis
    glia-activating factor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013518.4NP_038546.2  fibroblast growth factor 9 precursor

      See identical proteins and their annotated locations for NP_038546.2

      Status: VALIDATED

      Source sequence(s)
      AI414273, AK041815, AK158782, BX512213
      Consensus CDS
      CCDS27164.1
      UniProtKB/Swiss-Prot
      P54130
      Related
      ENSMUSP00000022545, OTTMUSP00000052767, ENSMUST00000022545, OTTMUST00000094754
      Conserved Domains (1) summary
      smart00442
      Location:60190
      FGF; Acidic and basic fibroblast growth factor family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      58072686..58112854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518554.3XP_006518617.1  fibroblast growth factor 9 isoform X1

      Conserved Domains (1) summary
      smart00442
      Location:18115
      FGF; Acidic and basic fibroblast growth factor family
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