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    Fah fumarylacetoacetate hydrolase [ Mus musculus (house mouse) ]

    Gene ID: 14085, updated on 8-May-2017
    Official Symbol
    Fahprovided by MGI
    Official Full Name
    fumarylacetoacetate hydrolaseprovided by MGI
    Primary source
    MGI:MGI:95482
    See related
    Ensembl:ENSMUSG00000030630 Vega:OTTMUSG00000025072
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Orthologs
    Location:
    7 D3; 7 48.36 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (84585159..84605942, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (91733669..91754452, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene cathepsin A pseudogene Neighboring gene predicted gene 2115 Neighboring gene zinc finger, AN1-type domain 6 Neighboring gene RIKEN cDNA 2610206C17 gene Neighboring gene transformation related protein 63 regulated like pseudogene Neighboring gene patatin-like phospholipase domain containing 8 pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    fumarylacetoacetase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fumarylacetoacetase activity ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    L-phenylalanine catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    arginine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    aromatic amino acid family metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    tyrosine catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    fumarylacetoacetase
    Names
    FAA
    beta-diketonase
    NP_034306.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010176.4NP_034306.2  fumarylacetoacetase

      See identical proteins and their annotated locations for NP_034306.2

      Status: VALIDATED

      Source sequence(s)
      AI848212, AK158808, BY265969, BY293890
      Consensus CDS
      CCDS21418.1
      UniProtKB/Swiss-Prot
      P35505
      Related
      ENSMUSP00000032865.8, OTTMUSP00000030308, ENSMUST00000032865.16, OTTMUST00000061684
      Conserved Domains (3) summary
      TIGR01266
      Location:2416
      fum_ac_acetase; fumarylacetoacetase
      pfam01557
      Location:124390
      FAA_hydrolase; Fumarylacetoacetate (FAA) hydrolase family
      pfam09298
      Location:15118
      FAA_hydrolase_N; Fumarylacetoacetase N-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      84585159..84605942 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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