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    S100a4 S100 calcium binding protein A4 [ Mus musculus (house mouse) ]

    Gene ID: 20198, updated on 13-Aug-2017
    Official Symbol
    S100a4provided by MGI
    Official Full Name
    S100 calcium binding protein A4provided by MGI
    Primary source
    MGI:MGI:1330282
    See related
    Ensembl:ENSMUSG00000001020 Vega:OTTMUSG00000022114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    42a; 18A2; Capl; FSp1; Mts1; pk9a; PeL98; metastasin
    Orthologs
    Location:
    3 F1; 3 39.27 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (90603770..90606045)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (90407692..90409967)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A16 Neighboring gene S100 calcium binding protein A3 Neighboring gene S100 calcium binding protein A2 Neighboring gene S100 calcium binding protein A5 Neighboring gene S100 calcium binding protein A6 (calcyclin)

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RAGE receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    protein S100-A4
    Names
    calvasculin
    metastatic cell protein
    placental calcium-binding protein
    protein 18A2
    protein Mts1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011311.2NP_035441.1  protein S100-A4

      See identical proteins and their annotated locations for NP_035441.1

      Status: VALIDATED

      Source sequence(s)
      AK160522, BX526220
      Consensus CDS
      CCDS17538.1
      UniProtKB/Swiss-Prot
      P07091
      UniProtKB/TrEMBL
      Q545V2
      Related
      ENSMUSP00000001046.5, OTTMUSP00000024898, ENSMUST00000001046.6, OTTMUST00000052492
      Conserved Domains (2) summary
      cd00213
      Location:490
      S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
      pfam13499
      Location:2576
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      90603770..90606045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501177.3XP_006501240.1  protein S100-A4 isoform X1

      See identical proteins and their annotated locations for XP_006501240.1

      UniProtKB/Swiss-Prot
      P07091
      UniProtKB/TrEMBL
      Q545V2
      Conserved Domains (2) summary
      cd00213
      Location:490
      S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
      pfam13499
      Location:2576
      EF-hand_7; EF-hand domain pair
    2. XM_006501178.2XP_006501241.1  protein S100-A4 isoform X1

      See identical proteins and their annotated locations for XP_006501241.1

      UniProtKB/Swiss-Prot
      P07091
      UniProtKB/TrEMBL
      Q545V2
      Conserved Domains (2) summary
      cd00213
      Location:490
      S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
      pfam13499
      Location:2576
      EF-hand_7; EF-hand domain pair
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