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    S100a10 S100 calcium binding protein A10 (calpactin) [ Mus musculus (house mouse) ]

    Gene ID: 20194, updated on 22-Apr-2017
    Official Symbol
    S100a10provided by MGI
    Official Full Name
    S100 calcium binding protein A10 (calpactin)provided by MGI
    Primary source
    MGI:MGI:1339468
    See related
    Ensembl:ENSMUSG00000041959 Vega:OTTMUSG00000022124
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    42C; p10; p11; CAL12; CLP11; Cal1l; AA409961; AL024248
    Orthologs
    Location:
    3 F2.1; 3 40.51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (93555068..93564645)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (93359039..93368567)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A11 Neighboring gene predicted gene, 29950 Neighboring gene predicted gene, 40093 Neighboring gene chymotrypsin C (caldecrin) pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cellular response to acid chemical IDA
    Inferred from Direct Assay
    more info
    PubMed 
    establishment of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane budding ISO
    Inferred from Sequence Orthology
    more info
     
    membrane raft assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    protein heterotetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extrinsic component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    protein S100-A10
    Names
    S100 calcium binding protein A10 (calgizzarin)
    S100 calcium-binding protein A10
    calcium binding protein A11 (calgizzarin)
    calpactin I light chain
    calpactin-1 light chain
    cellular ligand of annexin II

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009112.2NP_033138.1  protein S100-A10

      See identical proteins and their annotated locations for NP_033138.1

      Status: VALIDATED

      Source sequence(s)
      AK161647, BU559648, D18288
      Consensus CDS
      CCDS38526.1
      UniProtKB/Swiss-Prot
      P08207
      UniProtKB/TrEMBL
      Q3TC45
      Related
      ENSMUSP00000036949.7, OTTMUSP00000024909, ENSMUST00000045756.13, OTTMUST00000052509
      Conserved Domains (1) summary
      cl08302
      Location:393
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      93555068..93564645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319508.1XP_017174997.1  protein S100-A10 isoform X1

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