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    HTZ1 histone H2AZ [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854150, updated on 9-Apr-2017
    Gene symbol
    HTZ1
    Gene description
    histone H2AZ
    Primary source
    SGD:S000005372
    Locus tag
    YOL012C
    Gene type
    protein coding
    RNA name
    histone H2AZ
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    HTA3
    See HTZ1 in Map Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (303579..303983, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene tRNA Neighboring gene E3 ubiquitin-protein ligase HRD1 Neighboring gene lysophospholipase Neighboring gene rRNA-processing endoribonuclease

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromatin binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin silencing at silent mating-type cassette IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    chromatin silencing at silent mating-type cassette IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    covalent chromatin modification IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear-transcribed mRNA catabolic process, non-stop decay IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear chromatin IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleosome IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    histone H2AZ
    NP_014631.1
    • Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      303579..303983 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183266.1NP_014631.1  TPA: histone H2AZ [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_014631.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q12692
      Conserved Domains (2) summary
      PTZ00017
      Location:7134
      PTZ00017; histone H2A; Provisional
      cd00074
      Location:11126
      H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
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