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    ergo-1 Endogenous-RNAi deficient arGOnaute [ Caenorhabditis elegans ]

    Gene ID: 178602, updated on 5-Nov-2017
    Gene symbol
    ergo-1
    Gene description
    Endogenous-RNAi deficient arGOnaute
    Primary source
    WormBase:WBGene00019971
    Locus tag
    CELE_R09A1.1
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (1008813..1018073)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    DEAD/H-box RNA helicase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    RNA interference IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    gene silencing by RNA IEA
    Inferred from Electronic Annotation
    more info
     
    production of siRNA involved in RNA interference IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    Endogenous-RNAi deficient arGOnaute
    Piwi-like protein ergo-1
    NP_001300164.1
    • Product from WormBase gene class ergo;
      Confirmed by transcript evidence
    NP_001300165.1
    • Product from WormBase gene class ergo;
      Partially confirmed by transcript evidence
    NP_001300166.1
    • Product from WormBase gene class ergo;
      Confirmed by transcript evidence
    NP_503362.2
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1008813..1018073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070961.7NP_503362.2  Piwi-like protein ergo-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503362.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O61931
      Conserved Domains (2) summary
      smart00949
      Location:421557
      PAZ; This domain is named PAZ after the proteins Piwi Argonaut and Zwille
      cd04657
      Location:5881080
      Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...
    2. NM_001313235.1NP_001300164.1  Endogenous-RNAi deficient arGOnaute [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AY23
      Conserved Domains (2) summary
      smart00949
      Location:14150
      PAZ; This domain is named PAZ after the proteins Piwi Argonaut and Zwille
      cl00628
      Location:181673
      Piwi-like; Piwi-like: PIWI domain. Domain found in proteins involved in RNA silencing. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The ...
    3. NM_001313236.1NP_001300165.1  Endogenous-RNAi deficient arGOnaute [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ASS5
      Conserved Domains (1) summary
      cl00628
      Location:30392
      Piwi-like; Piwi-like: PIWI domain. Domain found in proteins involved in RNA silencing. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The ...
    4. NM_001313237.1NP_001300166.1  Endogenous-RNAi deficient arGOnaute [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AV28
      Conserved Domains (1) summary
      cl00628
      Location:1269
      Piwi-like; Piwi-like: PIWI domain. Domain found in proteins involved in RNA silencing. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The ...
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