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    cdh5 cadherin 5 [ Danio rerio (zebrafish) ]

    Gene ID: 445471, updated on 18-Mar-2017
    Official Symbol
    cdh5provided by ZNC
    Official Full Name
    cadherin 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040816-1
    See related
    Ensembl:ENSDARG00000075549 Vega:OTTDARG00000042914
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    wu:fc88a07
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    105 current GRCz10 (GCF_000002035.5) 7 NC_007118.6 (44106370..44128657)
    103 previous assembly Zv9 (GCF_000002035.4) 7 NC_007118.5 (45433470..45455757)

    Chromosome 7 - NC_007118.6Genomic Context describing neighboring genes Neighboring gene cadherin 11, type 2, OB-cadherin (osteoblast) Neighboring gene uncharacterized LOC108190800 Neighboring gene si:ch211-189a15.5 Neighboring gene brain expressed, associated with NEDD4, 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blood vessel lumenization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    endothelial tube lumen extension involved in blood vessel lumen ensheathment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    cadherin-5
    Names
    VE-cadherin (vascular epithelium)
    cadherin 5, type 2, VE-cadherin (vascular epithelium)
    fc88a07
    type 2
    vascular endothelial cadherin
    vecdn

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003983.1NP_001003983.1  cadherin-5 precursor

      See identical proteins and their annotated locations for NP_001003983.1

      Status: PROVISIONAL

      Source sequence(s)
      AY496430
      UniProtKB/TrEMBL
      Q68SP4
      Related
      ENSDARP00000104309, OTTDARP00000048510, ENSDART00000108766, OTTDART00000062029
      Conserved Domains (3) summary
      cd11304
      Location:160257
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:86153
      CA; Cadherin repeats
      pfam01049
      Location:630757
      Cadherin_C; Cadherin cytoplasmic region

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz10 Primary Assembly

    Genomic

    1. NC_007118.6 Reference GRCz10 Primary Assembly

      Range
      44106370..44128657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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