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    Kcne2 potassium voltage-gated channel, Isk-related subfamily, gene 2 [ Mus musculus (house mouse) ]

    Gene ID: 246133, updated on 9-Jul-2017
    Official Symbol
    Kcne2provided by MGI
    Official Full Name
    potassium voltage-gated channel, Isk-related subfamily, gene 2provided by MGI
    Primary source
    MGI:MGI:1891123
    See related
    Ensembl:ENSMUSG00000039672 Vega:OTTMUSG00000019966
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MiRP1; AW048273; 2200002I16Rik
    Orthologs
    Location:
    16; 16 C4
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (92292389..92298133)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (92292634..92298374)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 29880 Neighboring gene predicted gene, 41497 Neighboring gene RIKEN cDNA 1700048M11 gene Neighboring gene small integral membrane protein 11 Neighboring gene RIKEN cDNA 4930563D23 gene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to delayed rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to inward rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    potassium channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    voltage-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    voltage-gated potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cardiac muscle cell action potential involved in contraction ISO
    Inferred from Sequence Orthology
    more info
     
    cellular protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to drug ISO
    Inferred from Sequence Orthology
    more info
     
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    membrane repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    membrane repolarization during action potential ISO
    Inferred from Sequence Orthology
    more info
     
    membrane repolarization during ventricular cardiac muscle cell action potential ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of delayed rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of voltage-gated potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of proteasomal protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of voltage-gated calcium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    potassium ion export ISO
    Inferred from Sequence Orthology
    more info
     
    potassium ion import ISO
    Inferred from Sequence Orthology
    more info
     
    potassium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    potassium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cyclic nucleotide-gated ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of delayed rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of heart rate by cardiac conduction ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of inward rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of membrane repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of potassium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of ventricular cardiac muscle cell membrane repolarization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of ventricular cardiac muscle cell membrane repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    ventricular cardiac muscle cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ventricular cardiac muscle cell action potential ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    voltage-gated potassium channel complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with voltage-gated potassium channel complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    potassium voltage-gated channel subfamily E member 2
    Names
    minK-related peptide 1
    minimum potassium ion channel related peptide 1
    potassium channel subunit beta MiRP1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134110.3NP_598871.1  potassium voltage-gated channel subfamily E member 2

      See identical proteins and their annotated locations for NP_598871.1

      Status: VALIDATED

      Source sequence(s)
      AK008619, AW048273
      Consensus CDS
      CCDS28333.1
      UniProtKB/Swiss-Prot
      Q9D808
      UniProtKB/TrEMBL
      A0A0R4J1J2
      Related
      ENSMUSP00000048849.3, OTTMUSP00000021545, ENSMUST00000047383.9, OTTMUST00000047580
      Conserved Domains (1) summary
      pfam02060
      Location:5097
      ISK_Channel; Slow voltage-gated potassium channel

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      92292389..92298133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523033.3XP_006523096.1  potassium voltage-gated channel subfamily E member 2 isoform X1

      See identical proteins and their annotated locations for XP_006523096.1

      UniProtKB/Swiss-Prot
      Q9D808
      UniProtKB/TrEMBL
      A0A0R4J1J2
      Related
      ENSMUSP00000109604.1, OTTMUSP00000021546, ENSMUST00000113971.1, OTTMUST00000047581
      Conserved Domains (1) summary
      pfam02060
      Location:5097
      ISK_Channel; Slow voltage-gated potassium channel
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