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    adgrg6 adhesion G protein-coupled receptor G6 [ Danio rerio (zebrafish) ]

    Gene ID: 561970, updated on 4-Aug-2017
    Official Symbol
    adgrg6provided by ZNC
    Official Full Name
    adhesion G protein-coupled receptor G6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-357
    See related
    Ensembl:ENSDARG00000054137 Vega:OTTDARG00000006046
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    gpr126; si:ch211-202p1.3
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    Location:
    chromosome: 20
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (37393136..37463309)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (37490257..37560430)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene connexin 23 Neighboring gene vesicle (multivesicular body) trafficking 1 Neighboring gene si:ch211-202p1.5 Neighboring gene transfer RNA phenylalanine (anticodon GAA) Neighboring gene uncharacterized LOC108180283 Neighboring gene human immunodeficiency virus type I enhancer binding protein 2a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    G-protein coupled receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    G-protein coupled receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    collagen binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular matrix binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    laminin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Schwann cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cAMP-mediated signaling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    ear development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ear development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heart trabecula formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    myelination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    myelination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    myelination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    myelination in peripheral nervous system IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    myelination in peripheral nervous system IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    myelination in peripheral nervous system ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    myelination of posterior lateral line nerve axons IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ossification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    peripheral nervous system myelin formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    semicircular canal fusion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    adhesion G-protein coupled receptor G6
    Names
    G-protein coupled receptor 126
    bge
    big ears
    lau
    lauscher
    unm st49
    unm_st49

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163291.1NP_001156763.1  adhesion G-protein coupled receptor G6 precursor

      See identical proteins and their annotated locations for NP_001156763.1

      Status: PROVISIONAL

      Source sequence(s)
      GQ202546
      UniProtKB/Swiss-Prot
      C6KFA3
      Related
      ENSDARP00000109070.2, ENSDART00000128321.2
      Conserved Domains (4) summary
      pfam00431
      Location:41146
      CUB; CUB domain
      pfam01825
      Location:788833
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:8491099
      7tm_4; Olfactory receptor
      cl22861
      Location:153336
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      37393136..37463309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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