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    LSM1 Lsm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853318, updated on 8-Oct-2017
    Gene symbol
    LSM1
    Gene description
    Lsm1p
    Primary source
    SGD:S000003660
    Locus tag
    YJL124C
    Gene type
    protein coding
    RNA name
    Lsm1p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SPB8
    See LSM1 in Map Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (187126..187644, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene putative hydrolase Neighboring gene tRNA 1-methyladenosine methyltransferase subunit GCD14 Neighboring gene Mtc1p Neighboring gene Alb1p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA cap binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    RNA cap binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    RNA cap binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    Lsm1-7-Pat1 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    P-body IEA
    Inferred from Electronic Annotation
    more info
     
    P-body IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA cap binding complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Lsm1p
    NP_012411.1
    • Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      187126..187644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181557.1NP_012411.1  TPA: Lsm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012411.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P47017
      Conserved Domains (1) summary
      cd01728
      Location:40115
      LSm1; Like-Sm protein 1
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