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    Sftpc surfactant associated protein C [ Mus musculus (house mouse) ]

    Gene ID: 20389, updated on 25-Apr-2017
    Official Symbol
    Sftpcprovided by MGI
    Official Full Name
    surfactant associated protein Cprovided by MGI
    Primary source
    MGI:MGI:109517
    See related
    Ensembl:ENSMUSG00000022097
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
    Orthologs
    Location:
    14 D2; 14 36.32 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (70520941..70524081, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (70920748..70923888, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene phytanoyl-CoA hydroxylase interacting protein Neighboring gene bone morphogenetic protein 1 Neighboring gene leucine-rich repeat LGI family, member 3 Neighboring gene receptor accessory protein 4

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    alveolar lamellar body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    multivesicular body ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    pulmonary surfactant-associated protein C
    Names
    pulmonary surfactant-associated proteolipid SPL(Val)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011359.2NP_035489.2  pulmonary surfactant-associated protein C precursor

      See identical proteins and their annotated locations for NP_035489.2

      Status: VALIDATED

      Source sequence(s)
      AC122268, BY773034, CJ093163, CJ237354
      Consensus CDS
      CCDS27254.1
      UniProtKB/TrEMBL
      Q6P8P8
      Related
      ENSMUSP00000022692.3, ENSMUST00000022692.3
      Conserved Domains (3) summary
      smart00019
      Location:1193
      SF_P; Pulmonary surfactant proteins
      smart01039
      Location:94193
      BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer
      pfam08999
      Location:193
      SP_C-Propep; Surfactant protein C, N terminal propeptide

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      70520941..70524081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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