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    rheb-1 GTP-binding protein Rheb homolog 1 [ Caenorhabditis elegans ]

    Gene ID: 176327, updated on 12-Oct-2017
    Gene symbol
    rheb-1
    Gene description
    GTP-binding protein Rheb homolog 1
    Primary source
    WormBase:WBGene00010038
    Locus tag
    CELE_F54C8.5
    Gene type
    protein coding
    RNA name
    GTP-binding protein Rheb homolog 1
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (9454710..9456009, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene SR Protein Kinase Neighboring gene hypothetical protein

    • Autophagy - animal, organism-specific biosystem (from KEGG)
      Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - animal, conserved biosystem (from KEGG)
      Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Metapathway Signal Transduction, organism-specific biosystem (from WikiPathways)
      Metapathway Signal Transduction, organism-specific biosystem
      Metapathway Signal Transduction
    • TOR signaling, organism-specific biosystem (from WikiPathways)
      TOR signaling, organism-specific biosystem
      TOR signaling
    • mTOR signaling pathway, organism-specific biosystem (from KEGG)
      mTOR signaling pathway, organism-specific biosystemThe mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 conta...
    • mTOR signaling pathway, conserved biosystem (from KEGG)
      mTOR signaling pathway, conserved biosystemThe mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 conta...

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    positive regulation of TOR signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    reproduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    GTP-binding protein Rheb homolog 1
    NP_499079.1
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9454710..9456009 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066678.3NP_499079.1  GTP-binding protein Rheb homolog 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499079.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34443
      Conserved Domains (2) summary
      smart00010
      Location:13177
      small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
      cd04137
      Location:13207
      RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
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