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    DES-1-LIKE fatty acid desaturase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825832, updated on 6-Apr-2018
    Gene symbol
    DES-1-LIKE
    Gene description
    fatty acid desaturase family protein
    Primary source
    Araport:AT4G04930
    Locus tag
    AT4G04930
    Gene type
    protein coding
    RNA name
    fatty acid desaturase family protein
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DES-1-LIKE TRANSMEMBRANE PROTEIN; T1J1.1; T1J1_1
    Summary
    Encodes a sphingolipid delta4-desaturase, involved in sphingolipid biosynthesis. Specifically expressed in floral tissues. Knockout mutants were devoid of sphinga-4,8-dienine in floral tissues.
    See DES-1-LIKE in Genome Data Viewer Map Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (2509053..2511145)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein Neighboring gene miscRNA Neighboring gene transducin family protein / WD-40 repeat family protein Neighboring gene thioredoxin family protein Neighboring gene allantoinase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    NM_116731.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    oxidoreductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    sphingolipid delta-4 desaturase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    sphingolipid delta-4 desaturase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    ceramide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    sphingolipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    fatty acid desaturase family protein
    NP_192402.1
    • DES-1-LIKE; FUNCTIONS IN: oxidoreductase activity, sphingolipid delta-4 desaturase activity; INVOLVED IN: sphingolipid biosynthetic process; LOCATED IN: integral to membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Sphingolipid delta4-desaturase, N-terminal (InterPro:IPR013866), Fatty acid desaturase, type 1 (InterPro:IPR005804), Sphingolipid delta4-desaturase (InterPro:IPR011388); Has 703 Blast hits to 697 proteins in 257 species: Archae - 0; Bacteria - 174; Metazoa - 227; Fungi - 120; Plants - 36; Viruses - 3; Other Eukaryotes - 143 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      2509053..2511145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116731.4NP_192402.1  fatty acid desaturase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192402.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZPH4
      Conserved Domains (3) summary
      PLN02579
      Location:11332
      PLN02579; sphingolipid delta-4 desaturase
      cd03508
      Location:40327
      Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
      pfam08557
      Location:2256
      Lipid_DES; Sphingolipid Delta4-desaturase (DES)
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