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    TOC159 translocon at the outer envelope membrane of chloroplasts 159 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827934, updated on 9-Jul-2017
    Gene symbol
    TOC159
    Gene description
    translocon at the outer envelope membrane of chloroplasts 159
    Primary source
    Araport:AT4G02510
    Locus tag
    AT4G02510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTOC159; PLASTID PROTEIN IMPORT 2; PPI2; T10P11.19; TOC160; TOC86; translocon at the outer envelope membrane of chloroplasts 159; TRANSLOCON AT THE OUTER ENVELOPE MEMBRANE OF CHLOROPLASTS 160; TRANSLOCON AT THE OUTER ENVELOPE MEMBRANE OF CHLOROPLASTS 86
    Summary
    An integral membrane GTPase that functions as a transit-sequence receptor required for the import of proteins necessary for chloroplast biogenesis. Located in the outer chloroplast membrane. Phosphorylation of the G-domains regulate translocon assembly.
    See TOC159 in Map Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (1104429..1111784)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene UDP-xylosyltransferase 2 Neighboring gene glutathione S-transferase PHI 2 Neighboring gene chloroplast thylakoid lumen protein Neighboring gene ncRNA Neighboring gene ncRNA

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    NM_001340383.1
    NM_001340384.1
    NM_001340385.1
    NM_116485.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    G-protein coupled receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transmembrane signaling receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    protein import into chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein targeting to chloroplast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein targeting to chloroplast IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    chloroplast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chloroplast ISM
    Inferred from Sequence Model
    more info
     
    chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chloroplast outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plastid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    translocon at the outer envelope membrane of chloroplasts 159
    NP_001319848.1
    • translocon at the outer envelope membrane of chloroplasts 159 (TOC159); FUNCTIONS IN: transmembrane receptor activity, GTPase activity; INVOLVED IN: protein targeting to chloroplast; LOCATED IN: chloroplast outer membrane, cytosol, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Chloroplast protein import component Toc86/159 (InterPro:IPR005690), AIG1 (InterPro:IPR006703); BEST Arabidopsis thaliana protein match is: multimeric translocon complex in the outer envelope membrane 132 (TAIR:AT2G16640.1); Has 20720 Blast hits to 13966 proteins in 1613 species: Archae - 439; Bacteria - 5942; Metazoa - 6041; Fungi - 2379; Plants - 1534; Viruses - 151; Other Eukaryotes - 4234 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1104429..1111784
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340383.1NP_001319848.1  translocon at the outer envelope membrane of chloroplasts 159 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81283
    2. NM_001340384.1NP_001328636.1  translocon at the outer envelope membrane of chloroplasts 159 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81283
    3. NM_116485.4NP_567242.2  translocon at the outer envelope membrane of chloroplasts 159 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567242.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81283
      Conserved Domains (3) summary
      cd01853
      Location:8251078
      Toc34_like; Translocon at the Outer-envelope membrane of Chloroplasts 34-like (Toc34-like)
      TIGR00993
      Location:7391503
      3a0901s04IAP86; chloroplast protein import component Toc86/159, G and M domains
      pfam11886
      Location:12251490
      TOC159_MAD; Translocase of chloroplast 159/132, membrane anchor domain
    4. NM_001340385.1NP_001328635.1  translocon at the outer envelope membrane of chloroplasts 159 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81283
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