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    CBK1 serine/threonine protein kinase CBK1 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855561, updated on 9-Apr-2017
    Gene symbol
    CBK1
    Gene description
    serine/threonine protein kinase CBK1
    Primary source
    SGD:S000005105
    Locus tag
    YNL161W
    Gene type
    protein coding
    RNA name
    serine/threonine protein kinase CBK1
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See CBK1 in Map Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (332597..334867)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ribosomal 60S subunit protein L42A Neighboring gene Ygp1p Neighboring gene Asi2p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    budding cell apical bud growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    budding cell apical bud growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell separation after cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment or maintenance of actin cytoskeleton polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment or maintenance of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of fungal-type cell wall organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular bud IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular bud neck IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular bud tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    incipient cellular bud site IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mating projection tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    prospore membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    serine/threonine protein kinase CBK1
    NP_014238.3
    • Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      332597..334867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182999.3NP_014238.3  TPA: serine/threonine protein kinase CBK1 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_014238.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53894
      Conserved Domains (2) summary
      smart00220
      Location:352672
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05629
      Location:350748
      STKc_NDR_like_fungal; Catalytic domain of Fungal Nuclear Dbf2-Related kinase-like Serine/Threonine Kinases
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