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    MSM1 methionine--tRNA ligase MSM1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853081, updated on 5-Nov-2017
    Gene symbol
    MSM1
    Gene description
    methionine--tRNA ligase MSM1
    Primary source
    SGD:S000003403
    Locus tag
    YGR171C
    Gene type
    protein coding
    RNA name
    methionine--tRNA ligase MSM1
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (840824..842551, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Lso2p Neighboring gene phosphatidylserine decarboxylase 2 Neighboring gene transporter YIP1 Neighboring gene Rbg2p

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    aminoacyl-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    methionine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    methionine-tRNA ligase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    methionyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
     
    methionyl-tRNA aminoacylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tRNA aminoacylation for protein translation IEA
    Inferred from Electronic Annotation
    more info
     
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Names
    methionine--tRNA ligase MSM1
    NP_011687.1
    • Mitochondrial methionyl-tRNA synthetase (MetRS); functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      840824..842551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181300.1NP_011687.1  TPA: methionine--tRNA ligase MSM1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011687.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P22438
      Conserved Domains (3) summary
      cd00814
      Location:16380
      MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
      TIGR00398
      Location:15550
      metG; methionine--tRNA ligase
      cl12020
      Location:392526
      Anticodon_Ia_like; Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains
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