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    Sctr secretin receptor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 81779, updated on 5-Nov-2017
    Official Symbol
    Sctrprovided by RGD
    Official Full Name
    secretin receptorprovided by RGD
    Primary source
    RGD:621342
    See related
    Ensembl:ENSRNOG00000049766
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    G-protein coupled receptor that binds secretin and induces cAMP production; mediates secretin induction of pancreatic secretion of bicarbonate, enzymes, and potassium ion [RGD, Feb 2006]
    Orthologs
    Location:
    13q11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (36039241..36090515)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 13 NC_005112.3 (41160339..41201354)

    Chromosome 13 - NC_005112.4Genomic Context describing neighboring genes Neighboring gene transmembrane protein 177 Neighboring gene cilia and flagella associated protein 221 Neighboring gene transmembrane protein 37 Neighboring gene hypothetical LOC288978 Neighboring gene diazepam binding inhibitor, acyl-CoA binding protein

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC93381

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptide binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptide binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    secretin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    brain development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cAMP biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasmic microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasmic microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    secretin receptor
    Names
    SCT-R

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031115.1NP_112377.1  secretin receptor precursor

      See identical proteins and their annotated locations for NP_112377.1

      Status: PROVISIONAL

      Source sequence(s)
      X59132
      UniProtKB/Swiss-Prot
      P23811
      Related
      ENSRNOP00000064579.2, ENSRNOT00000072088.2
      Conserved Domains (2) summary
      smart00008
      Location:62132
      HormR; Domain present in hormone receptors
      pfam00002
      Location:139384
      7tm_2; 7 transmembrane receptor (Secretin family)

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005112.4 Reference Rnor_6.0 Primary Assembly

      Range
      36039241..36090515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000081.1 Alternate Rn_Celera

      Range
      31000848..31067419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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