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    CSK c-src tyrosine kinase [ Gallus gallus (chicken) ]

    Gene ID: 396396, updated on 9-Apr-2017
    Symbol
    CSKprovided by CGNC
    Full Name
    c-src tyrosine kinaseprovided by CGNC
    Primary source
    CGNC:902
    See related
    Ensembl:ENSGALG00000031270
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Gallus_gallus-5.0 (GCF_000002315.4) 10 NC_006097.4 (2358434..2366314, complement)
    102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 10 NC_006097.3 (1926024..1929584, complement)

    Chromosome 10 - NC_006097.4Genomic Context describing neighboring genes Neighboring gene unc-51 like kinase 3 Neighboring gene complexin 3 Neighboring gene cytochrome P450, family 1, subfamily A, polypeptide 2 Neighboring gene cytochrome P450, family 1, subfamily A, polypeptide 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    non-membrane spanning protein tyrosine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
     
    adherens junction organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    central nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptidyl-tyrosine autophosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of Fc receptor mediated stimulatory signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    transmembrane receptor protein tyrosine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    extrinsic component of cytoplasmic side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    tyrosine-protein kinase CSK
    Names
    C-Src kinase
    protein kinase
    src kinase
    NP_990756.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205425.1NP_990756.1  tyrosine-protein kinase CSK

      See identical proteins and their annotated locations for NP_990756.1

      Status: PROVISIONAL

      Source sequence(s)
      M85039
      UniProtKB/Swiss-Prot
      P41239
      Related
      ENSGALP00000057776.1, ENSGALT00000047956.1
      Conserved Domains (4) summary
      cd09937
      Location:78175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:1167
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase
      smart00221
      Location:195440
      STYKc; Protein kinase; unclassified specificity
      cl21453
      Location:188443
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Gallus_gallus-5.0 Primary Assembly

    Genomic

    1. NC_006097.4 Reference Gallus_gallus-5.0 Primary Assembly

      Range
      2358434..2366314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015278794.1XP_015134280.1  tyrosine-protein kinase CSK isoform X1

      UniProtKB/TrEMBL
      A0A1D5PXS9
      Conserved Domains (4) summary
      cd09937
      Location:78175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:1167
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase
      smart00221
      Location:195440
      STYKc; Protein kinase; unclassified specificity
      cl21453
      Location:188443
      PKc_like; Protein Kinases, catalytic domain
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