Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Cdx2 caudal type homeobox 2 [ Mus musculus (house mouse) ]

    Gene ID: 12591, updated on 27-Jun-2017
    Official Symbol
    Cdx2provided by MGI
    Official Full Name
    caudal type homeobox 2provided by MGI
    Primary source
    MGI:MGI:88361
    See related
    Ensembl:ENSMUSG00000029646 Vega:OTTMUSG00000037225
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cdx-2
    Orthologs
    Location:
    5 G3; 5 86.86 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (147300900..147307249, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (148112476..148118825, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene microRNA 7k Neighboring gene predicted gene, 35112 Neighboring gene ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase Neighboring gene predicted gene, 29778

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    animal organ morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    anterior/posterior axis specification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    anterior/posterior pattern specification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    blastocyst development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blood vessel development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endosome to lysosome transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment or maintenance of epithelial cell apical/basal polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intestinal epithelial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    labyrinthine layer development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    pattern specification process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    placenta development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of somitogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    somatic stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    trophectodermal cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trophectodermal cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcriptional repressor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    homeobox protein CDX-2
    Names
    caudal type homeo box 2
    caudal-type homeobox protein 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007673.3NP_031699.2  homeobox protein CDX-2

      See identical proteins and their annotated locations for NP_031699.2

      Status: PROVISIONAL

      Source sequence(s)
      AK049566
      Consensus CDS
      CCDS19878.1
      UniProtKB/Swiss-Prot
      P43241
      UniProtKB/TrEMBL
      Q543L9
      Related
      ENSMUSP00000031650.3, OTTMUSP00000053588, ENSMUST00000031650.3, OTTMUST00000095994
      Conserved Domains (2) summary
      pfam00046
      Location:189241
      Homeobox; Homeobox domain
      pfam04731
      Location:13170
      Caudal_act; Caudal like protein activation region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      147300900..147307249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center