Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Casc1 cancer susceptibility candidate 1 [ Mus musculus (house mouse) ]

    Gene ID: 320662, updated on 25-May-2017
    Official Symbol
    Casc1provided by MGI
    Official Full Name
    cancer susceptibility candidate 1provided by MGI
    Primary source
    MGI:MGI:2444480
    See related
    Ensembl:ENSMUSG00000043541 Vega:OTTMUSG00000023460
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Las1; A230084G12Rik
    Orthologs
    Location:
    6 G3; 6 77.37 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (145174872..145211017, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (145123392..145159490, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene branched chain aminotransferase 1, cytosolic Neighboring gene predicted gene, 26666 Neighboring gene predicted gene, 38925 Neighboring gene lymphoid-restricted membrane protein Neighboring gene predicted gene 15543 Neighboring gene electron transfer flavoprotein regulatory factor 1 Neighboring gene Kirsten rat sarcoma viral oncogene homolog

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    beta-tubulin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    microtubule-based movement ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    colocalizes_with cytoplasmic microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    protein CASC1
    Names
    cancer susceptibility candidate gene 1 protein homolog
    cancer susceptibility candidate protein 1
    lung adenoma susceptibility 1
    lung adenoma susceptibility protein 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177222.4NP_796196.3  protein CASC1

      See identical proteins and their annotated locations for NP_796196.3

      Status: VALIDATED

      Source sequence(s)
      AY485608, BB374869, CJ202396
      Consensus CDS
      CCDS39705.1
      UniProtKB/Swiss-Prot
      Q6TDU8
      UniProtKB/TrEMBL
      A0A0R4J0S9
      Related
      ENSMUSP00000062279.7, OTTMUSP00000027475, ENSMUST00000060797.9, OTTMUST00000057040
      Conserved Domains (2) summary
      pfam12366
      Location:244469
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      145174872..145211017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321646.1XP_017177135.1  protein CASC1 isoform X10

    2. XM_006506973.2XP_006507036.1  protein CASC1 isoform X7

      Conserved Domains (2) summary
      pfam12366
      Location:152377
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:4137
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    3. XM_006506971.2XP_006507034.1  protein CASC1 isoform X5

      Conserved Domains (2) summary
      pfam12366
      Location:198423
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39183
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    4. XM_017321645.1XP_017177134.1  protein CASC1 isoform X9

    5. XM_011241588.1XP_011239890.1  protein CASC1 isoform X1

      Conserved Domains (2) summary
      pfam12366
      Location:233458
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39218
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    6. XM_006506974.2XP_006507037.1  protein CASC1 isoform X8

      Conserved Domains (2) summary
      pfam12366
      Location:377545
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    7. XM_006506972.2XP_006507035.1  protein CASC1 isoform X6

      Conserved Domains (2) summary
      pfam12366
      Location:429597
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    8. XM_006506970.2XP_006507033.1  protein CASC1 isoform X3

      Related
      ENSMUSP00000107357.1, OTTMUSP00000030948, ENSMUST00000111728.7, OTTMUST00000057044
      Conserved Domains (2) summary
      pfam12366
      Location:244469
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    9. XM_011241593.1XP_011239895.1  protein CASC1 isoform X4

      Conserved Domains (2) summary
      pfam12366
      Location:244423
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    10. XM_011241590.1XP_011239892.1  protein CASC1 isoform X2

      See identical proteins and their annotated locations for XP_011239892.1

      Conserved Domains (2) summary
      pfam12366
      Location:231456
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:26216
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    11. XM_011241591.1XP_011239893.1  protein CASC1 isoform X2

      See identical proteins and their annotated locations for XP_011239893.1

      Conserved Domains (2) summary
      pfam12366
      Location:231456
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:26216
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    12. XM_011241592.1XP_011239894.1  protein CASC1 isoform X2

      See identical proteins and their annotated locations for XP_011239894.1

      Conserved Domains (2) summary
      pfam12366
      Location:231456
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:26216
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    13. XM_011241589.1XP_011239891.1  protein CASC1 isoform X2

      See identical proteins and their annotated locations for XP_011239891.1

      Conserved Domains (2) summary
      pfam12366
      Location:231456
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:26216
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    14. XM_011241594.1XP_011239896.1  protein CASC1 isoform X11

      Conserved Domains (1) summary
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    15. XM_006506978.2XP_006507041.1  protein CASC1 isoform X12

      Conserved Domains (1) summary
      pfam15927
      Location:39229
      Casc1_N; Cancer susceptibility candidate 1 N-terminus

    RNA

    1. XR_001785141.1 RNA Sequence

      Related
      ENSMUST00000111727.7
    2. XR_001785140.1 RNA Sequence

    3. XR_378098.2 RNA Sequence

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_166305.2 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      1692990..1729076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center