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    DSD1 D-serine ammonia-lyase DSD1 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 852679, updated on 9-Apr-2017
    Gene symbol
    DSD1
    Gene description
    D-serine ammonia-lyase DSD1
    Primary source
    SGD:S000003164
    Locus tag
    YGL196W
    Gene type
    protein coding
    RNA name
    D-serine ammonia-lyase DSD1
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See DSD1 in Map Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (129883..131169)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Yip4p Neighboring gene Mds3p Neighboring gene Gcn1p Neighboring gene hypothetical protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Glycine, serine and threonine metabolism, organism-specific biosystem (from KEGG)
      Glycine, serine and threonine metabolism, organism-specific biosystemSerine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In ...
    • Glycine, serine and threonine metabolism, conserved biosystem (from KEGG)
      Glycine, serine and threonine metabolism, conserved biosystemSerine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In ...
    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    D-serine ammonia-lyase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    D-serine ammonia-lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    D-serine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    Names
    D-serine ammonia-lyase DSD1
    NP_011319.2
    • D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a reaction dependent on pyridoxal 5'-phosphate and zinc; may play a role in D-serine detoxification; L-serine is not a substrate

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      129883..131169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181061.1NP_011319.2  TPA: D-serine ammonia-lyase DSD1 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_011319.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53095
      Conserved Domains (2) summary
      cd06817
      Location:13428
      PLPDE_III_DSD; Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Eukaryotic D-Serine Dehydratase
      COG3616
      Location:7425
      Dsd1; D-serine deaminase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]
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