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    Noct nocturnin [ Mus musculus (house mouse) ]

    Gene ID: 12457, updated on 27-Jan-2018
    Official Symbol
    Noctprovided by MGI
    Official Full Name
    nocturninprovided by MGI
    Primary source
    MGI:MGI:109382
    See related
    Ensembl:ENSMUSG00000023087 Vega:OTTMUSG00000027519
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccr4; Ccrn4l; AU043840
    Expression
    Ubiquitous expression in placenta adult (RPKM 54.9), colon adult (RPKM 24.9) and 28 other tissues See more
    Orthologs
    See Noct in Genome Data Viewer
    Location:
    3; 3 C
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (51224447..51251654)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (51028369..51055576)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35891 Neighboring gene predicted gene, 40044 Neighboring gene RIKEN cDNA 4930577N17 gene Neighboring gene E74-like factor 2 Neighboring gene nuclear encoded tRNA proline 7 (anticodon TGG)

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    poly(A)-specific ribonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    poly(A)-specific ribonuclease activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    circadian regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    circadian rhythm IEA
    Inferred from Electronic Annotation
    more info
     
    circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cytoplasmic mRNA processing body assembly IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    deadenylation-dependent decapping of nuclear-transcribed mRNA IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of osteoblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to extracellular stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to lipopolysaccharide IDA
    Inferred from Direct Assay
    more info
    PubMed 
    rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    nocturnin
    Names
    CCR4 carbon catabolite repression 4-like
    CCR4 protein homolog
    carbon catabolite repression 4 homolog
    carbon catabolite repression 4-like protein
    circadian deadenylase NOC
    NP_033964.1
    XP_006501019.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009834.2NP_033964.1  nocturnin

      See identical proteins and their annotated locations for NP_033964.1

      Status: VALIDATED

      Source sequence(s)
      AK084516, AK087790, BB261546
      Consensus CDS
      CCDS17336.1
      UniProtKB/Swiss-Prot
      O35710
      UniProtKB/TrEMBL
      B2RTJ8
      Related
      ENSMUSP00000023849.8, OTTMUSP00000034381, ENSMUST00000023849.14, OTTMUST00000068124
      Conserved Domains (1) summary
      cd09096
      Location:142421
      Deadenylase_nocturnin; C-terminal deadenylase domain of nocturnin and related domains

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      51224447..51251654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500956.1XP_006501019.1  nocturnin isoform X1

      Conserved Domains (1) summary
      cd09096
      Location:85364
      Deadenylase_nocturnin; C-terminal deadenylase domain of nocturnin and related domains
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