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    tbx-2 T-box protein 2 [ Caenorhabditis elegans ]

    Gene ID: 175698, updated on 9-Jul-2017
    Gene symbol
    tbx-2
    Gene description
    T-box protein 2
    Primary source
    WormBase:WBGene00006543
    Locus tag
    CELE_F21H11.3
    Gene type
    protein coding
    RNA name
    T-box protein 2
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See tbx-2 in Map Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (5131337..5136176, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene DumPY: shorter than wild-type Neighboring gene Sensory AXon guidance Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene hypothetical protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription factor activity, sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor activity, sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    locomotion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nematode larval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    nematode larval development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    olfactory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pharyngeal muscle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Names
    T-box protein 2
    NP_498088.1
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5131337..5136176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065687.3NP_498088.1  T-box protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498088.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19691
      Conserved Domains (1) summary
      cd00182
      Location:60245
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
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