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    Fabp4 fatty acid binding protein 4, adipocyte [ Mus musculus (house mouse) ]

    Gene ID: 11770, updated on 12-Mar-2017
    Official Symbol
    Fabp4provided by MGI
    Official Full Name
    fatty acid binding protein 4, adipocyteprovided by MGI
    Primary source
    MGI:MGI:88038
    See related
    Ensembl:ENSMUSG00000062515 Vega:OTTMUSG00000051458
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ap2; Lbpl; 422/aP2; ALBP/Ap2
    Location:
    3 A1; 3 2.56 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (10204342..10208602, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (10204342..10208576, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene peripheral myelin protein 2 Neighboring gene fatty acid binding protein 9, testis Neighboring gene fatty acid binding protein 12 Neighboring gene uncharacterized LOC102636393 Neighboring gene inositol (myo)-1(or 4)-monophosphatase 1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    fatty acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    brown fat cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to lithium ion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to tumor necrosis factor IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cholesterol homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cytokine production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fatty acid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    white fat cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    fatty acid-binding protein, adipocyte
    Names
    3T3-L1 lipid-binding protein
    A-FABP
    AFABP
    ALBP
    P15
    P2 adipocyte protein
    adipocyte lipid-binding protein
    adipocyte protein aP2
    adipocyte-type fatty acid-binding protein
    fatty acid-binding protein 4
    myelin P2 protein homolog
    protein 422

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024406.2NP_077717.1  fatty acid-binding protein, adipocyte

      See identical proteins and their annotated locations for NP_077717.1

      Status: VALIDATED

      Source sequence(s)
      AA066537, AK003143, BY081693
      Consensus CDS
      CCDS17238.1
      UniProtKB/Swiss-Prot
      P04117
      UniProtKB/TrEMBL
      Q542H7
      Related
      ENSMUSP00000029041, OTTMUSP00000069766, ENSMUST00000029041, OTTMUST00000130031
      Conserved Domains (1) summary
      pfam00061
      Location:6132
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      10204342..10208602 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530048.3XP_006530111.1  fatty acid-binding protein, adipocyte isoform X1

      Conserved Domains (1) summary
      pfam00061
      Location:683
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
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