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    DRD2 dopamine receptor D2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694181, updated on 3-Apr-2017
    Gene symbol
    DRD2
    Gene description
    dopamine receptor D2
    See related
    Ensembl:ENSMMUG00000014334
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    Location:
    chromosome: 14
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    102 current Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (106270721..106337408, complement)
    Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 14 NC_007871.1 (111874385..111941554, complement)

    Chromosome 14 - NC_027906.1Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 12 Neighboring gene ankyrin repeat and kinase domain containing 1 Neighboring gene uncharacterized LOC106993478 Neighboring gene transmembrane protease, serine 5

    • Alcoholism, organism-specific biosystem (from KEGG)
      Alcoholism, organism-specific biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Alcoholism, conserved biosystem (from KEGG)
      Alcoholism, conserved biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Cocaine addiction, organism-specific biosystem (from KEGG)
      Cocaine addiction, organism-specific biosystemDrug addiction is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behavior persists despite serious negative consequences.There is strong evidence that the dopaminergic...
    • Cocaine addiction, conserved biosystem (from KEGG)
      Cocaine addiction, conserved biosystemDrug addiction is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behavior persists despite serious negative consequences.There is strong evidence that the dopaminergic...
    • Dopaminergic synapse, organism-specific biosystem (from KEGG)
      Dopaminergic synapse, organism-specific biosystemDopamine (DA) is an important and prototypical slow neurotransmitter in the mammalian brain, where it controls a variety of functions including locomotor activity, motivation and reward, learning an...
    • Dopaminergic synapse, conserved biosystem (from KEGG)
      Dopaminergic synapse, conserved biosystemDopamine (DA) is an important and prototypical slow neurotransmitter in the mammalian brain, where it controls a variety of functions including locomotor activity, motivation and reward, learning an...
    • Gap junction, organism-specific biosystem (from KEGG)
      Gap junction, organism-specific biosystemGap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels'...
    • Gap junction, conserved biosystem (from KEGG)
      Gap junction, conserved biosystemGap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels'...
    • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
      Neuroactive ligand-receptor interaction, organism-specific biosystem
      Neuroactive ligand-receptor interaction
    • Neuroactive ligand-receptor interaction, conserved biosystem (from KEGG)
      Neuroactive ligand-receptor interaction, conserved biosystem
      Neuroactive ligand-receptor interaction
    • Parkinson's disease, organism-specific biosystem (from KEGG)
      Parkinson's disease, organism-specific biosystemParkinson's disease (PD) is a progressive neurodegenerative movement disorder that results primarily from the death of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Mutations...
    • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
      Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
    • Rap1 signaling pathway, conserved biosystem (from KEGG)
      Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
    • cAMP signaling pathway, organism-specific biosystem (from KEGG)
      cAMP signaling pathway, organism-specific biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
    • cAMP signaling pathway, conserved biosystem (from KEGG)
      cAMP signaling pathway, conserved biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...

    Markers

    Homology

    Preferred Names
    D(2) dopamine receptor
    Names
    D(2) dopamine receptor isoform long

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_8.0.1 Primary Assembly

    Genomic

    1. NC_027906.1 Reference Mmul_8.0.1 Primary Assembly

      Range
      106270721..106337408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001085336.3XP_001085336.1  D(2) dopamine receptor isoform X2

      See identical proteins and their annotated locations for XP_001085336.1

      UniProtKB/TrEMBL
      F7CYJ5
      Related
      ENSMMUP00000018833.2, ENSMMUT00000020121.3
      Conserved Domains (3) summary
      pfam00001
      Location:51397
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam08688
      Location:229297
      ASD1; Apx/Shroom domain ASD1
      cl21561
      Location:49234
      7tm_4; Olfactory receptor
    2. XM_001085571.3XP_001085571.1  D(2) dopamine receptor isoform X1

      See identical proteins and their annotated locations for XP_001085571.1

      UniProtKB/TrEMBL
      F7CYH8
      Related
      ENSMMUP00000018834.2, ENSMMUT00000020122.3
      Conserved Domains (2) summary
      pfam00001
      Location:51426
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:49234
      7tm_4; Olfactory receptor
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