Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Maoa monoamine oxidase A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29253, updated on 8-Oct-2017
    Official Symbol
    Maoaprovided by RGD
    Official Full Name
    monoamine oxidase Aprovided by RGD
    Primary source
    RGD:61898
    See related
    Ensembl:ENSRNOG00000002848
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mao
    Summary
    enzyme involved in the oxidative deamination of biogenic and xenobiotic amines [RGD, Feb 2006]
    Orthologs
    Location:
    Xq11
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (6554698..6620722, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (7373101..7439125, complement)

    Chromosome X - NC_005120.4Genomic Context describing neighboring genes Neighboring gene similar to 60S ribosomal protein L29 (P23) Neighboring gene monoamine oxidase B Neighboring gene similar to 60S ribosomal protein L29 (P23) Neighboring gene NDP, norrin cystine knot growth factor

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    flavin adenine dinucleotide binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    flavin adenine dinucleotide binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    primary amine oxidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    primary amine oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    primary amine oxidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    primary amine oxidase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    serotonin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    serotonin binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    catecholamine catabolic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    dopamine catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    dopamine catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neurotransmitter catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    phenylethylamine metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phenylethylamine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    serotonin metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    serotonin metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    amine oxidase [flavin-containing] A
    Names
    MAO-A
    monoamine oxidase type A
    NP_387502.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033653.1NP_387502.1  amine oxidase [flavin-containing] A

      See identical proteins and their annotated locations for NP_387502.1

      Status: VALIDATED

      Source sequence(s)
      FM031063, FM037037, FM044630, FM098276, FM101032, FM117485, FM132632
      UniProtKB/TrEMBL
      G3V9Z3
      Related
      ENSRNOP00000063784.1, ENSRNOT00000066674.2
      Conserved Domains (2) summary
      COG1231
      Location:15463
      YobN; Monoamine oxidase [Amino acid transport and metabolism]
      pfam13450
      Location:1884
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005120.4 Reference Rnor_6.0 Primary Assembly

      Range
      6554698..6620722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000089.1 Alternate Rn_Celera

      Range
      6522076..6588367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center