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    Cd24a CD24a antigen [ Mus musculus (house mouse) ]

    Gene ID: 12484, updated on 26-Nov-2016
    Official Symbol
    Cd24aprovided by MGI
    Official Full Name
    CD24a antigenprovided by MGI
    Primary source
    MGI:MGI:88323
    See related
    Ensembl:ENSMUSG00000047139
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HSA; Cd24; Ly-52; nectadrin
    Orthologs
    Location:
    10 B2; 10 23.01 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (43579169..43584265)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (43298975..43304071)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700021F05 gene Neighboring gene presequence translocase-asssociated motor 16 homolog pseudogene Neighboring gene RIKEN cDNA F830002L21 gene Neighboring gene ribosomal protein L26, pseudogene 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carbohydrate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein tyrosine kinase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    T cell costimulation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    apoptotic mitochondrial changes IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apoptotic nuclear changes IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell activation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell surface receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chemokine receptor transport out of membrane raft IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cholesterol homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
    Inferred from Direct Assay
    more info
    PubMed 
    homotypic cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leukocyte cell-cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    leukocyte migration involved in inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of B cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of T cell homeostatic proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of erythrocyte aggregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of erythrocyte clearance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of neuroblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transforming growth factor beta3 production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    neuromuscular synaptic transmission IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuromuscular synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron projection development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of B cell apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of MAP kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of T cell homeostatic proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of T cell mediated immune response to tumor cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of activated T cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of alpha-beta T cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of alpha-beta T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of calcium-mediated signaling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell adhesion mediated by integrin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell adhesion mediated by integrin IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell-cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell-cell adhesion mediated by integrin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cytosolic calcium ion concentration ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of inflammatory response to antigenic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of integrin activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of integrin activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of neuron projection development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of neuron projection development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of peptidyl-tyrosine phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pre-B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of cell-cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cell-cell adhesion mediated by integrin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cytokine-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    respiratory burst ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    response to estrogen ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    response to hypoxia ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    response to molecule of bacterial origin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synaptic vesicle endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    anchored component of external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    anchored component of external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    anchored component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ciliary membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    membrane raft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane raft ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    microvillus membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    signal transducer CD24
    Names
    M1/69-J11D heat stable antigen
    R13-Ag
    X62 heat stable antigen
    cluster of differentiation 24
    heat stable antigen
    lymphocyte antigen 52

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009846.2NP_033976.1  signal transducer CD24 precursor

      See identical proteins and their annotated locations for NP_033976.1

      Status: VALIDATED

      Source sequence(s)
      AA154829, AK014279, AK133869
      Consensus CDS
      CCDS23821.1
      UniProtKB/Swiss-Prot
      P24807
      UniProtKB/TrEMBL
      Q3THW4, Q8CEU3
      Related
      ENSMUSP00000057983, ENSMUST00000058714
      Conserved Domains (1) summary
      pfam14984
      Location:2663
      CD24; CD24 protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      43579169..43584265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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