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    Slc2a1 solute carrier family 2 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24778, updated on 8-Apr-2018
    Official Symbol
    Slc2a1provided by RGD
    Official Full Name
    solute carrier family 2 member 1provided by RGD
    Primary source
    RGD:3704
    See related
    Ensembl:ENSRNOG00000007284
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    GTG1; Gtg3; GLUTB; Glut1; RATGTG1
    Summary
    transporter for glucose and other hexoses; may be involved in response to osmotic and metabolic stress [RGD, Feb 2006]
    Expression
    Biased expression in Brain (RPKM 185.1), Kidney (RPKM 121.2) and 9 other tissues See more
    Orthologs
    Location:
    5q36
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (138154677..138182897)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (141964114..141992634)

    Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 pseudogene Neighboring gene uncharacterized LOC108351021 Neighboring gene zinc finger protein 691 Neighboring gene erythroblast membrane-associated protein

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    D-glucose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    D-glucose transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    dehydroascorbic acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dehydroascorbic acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    glucose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glucose transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    glucose transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein self-association ISO
    Inferred from Sequence Orthology
    more info
     
    protein self-association ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    xenobiotic transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular hyperosmotic response IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to glucose starvation IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to glucose starvation ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to mechanical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cerebral cortex development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    dehydroascorbic acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dehydroascorbic acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    female pregnancy IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    glucose transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glucose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    glucose transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to Thyroglobulin triiodothyronine IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to insulin IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    xenobiotic transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    Z disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    caveola IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cortical actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    cortical actin cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    female pronucleus IEA
    Inferred from Electronic Annotation
    more info
     
    female pronucleus ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intercalated disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    melanosome IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    midbody IEA
    Inferred from Electronic Annotation
    more info
     
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    sarcolemma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with sarcolemma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    solute carrier family 2, facilitated glucose transporter member 1
    Names
    GLUT-1
    Solute carrier family 2 a 1 (facilitated glucose transporter) brain
    glucose transporter type 1, erythrocyte/brain
    solute carrier family 2 (facilitated glucose transporter), member 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138827.1NP_620182.1  solute carrier family 2, facilitated glucose transporter member 1

      See identical proteins and their annotated locations for NP_620182.1

      Status: PROVISIONAL

      Source sequence(s)
      M13979
      UniProtKB/Swiss-Prot
      P11167
      Related
      ENSRNOP00000061340.1, ENSRNOT00000064452.2
      Conserved Domains (2) summary
      cd06174
      Location:62450
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:19467
      Sugar_tr; Sugar (and other) transporter

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

      Range
      138154677..138182897
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000073.1 Alternate Rn_Celera

      Range
      131243786..131272021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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