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    EMB2757 Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829108, updated on 27-Mar-2017
    Gene symbol
    EMB2757
    Gene description
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    Araport:AT4G29860
    Locus tag
    AT4G29860
    Gene type
    protein coding
    RNA name
    Transducin/WD40 repeat-like superfamily protein
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALT2; ALUMINUM TOLERANT 2; AtDSE1; DECREASED SIZE EXCLUSION LIMIT 1; DSE1; EMBRYO DEFECTIVE 2757; F27B13.100; F27B13_100; TAN; TANMEI
    Summary
    Encodes a WD repeat protein with seven WD repeat motifs, predicted to function in protein-protein interaction. Mutations caused defects in both embryo and seedling development.
    Location:
    chromosome: 4
    Exon count:
    15
    Sequence:
    Chromosome: 4; NC_003075.7 (14601698..14605810, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene Pyridoxal-5'-phosphate-dependent enzyme family protein Neighboring gene transmembrane protein (DUF872) Neighboring gene ncRNA Neighboring gene Oligosaccharyltransferase complex/magnesium transporter family protein Neighboring gene plant intracellular ras group-related LRR 7

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Homology

    NM_119132.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    nucleotide binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    DNA integrity checkpoint IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acquisition of desiccation tolerance in seed IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
     
    plant ovule development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasmodesma organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasmodesmata-mediated intercellular transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pollen development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell cycle arrest IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of root development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to aluminum ion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to cisplatin IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISM
    Inferred from Sequence Model
    more info
     
    Names
    Transducin/WD40 repeat-like superfamily protein
    NP_194715.2
    • EMBRYO DEFECTIVE 2757 (EMB2757); FUNCTIONS IN: nucleotide binding; INVOLVED IN: acquisition of desiccation tolerance, embryo development, embryo development ending in seed dormancy; LOCATED IN: CUL4 RING ubiquitin ligase complex; EXPRESSED IN: stem, rosette leaf, fruit, root, cultured cell; EXPRESSED DURING: F mature embryo stage, D bilateral stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT1G11160.1); Has 24053 Blast hits to 12842 proteins in 620 species: Archae - 42; Bacteria - 6408; Metazoa - 6694; Fungi - 5230; Plants - 2600; Viruses - 0; Other Eukaryotes - 3079 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14601698..14605810 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119132.3NP_194715.2  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194715.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3MV14
      Conserved Domains (3) summary
      COG2319
      Location:13379
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:216260
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:9378
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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