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    Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 [ Mus musculus (house mouse) ]

    Gene ID: 21944, updated on 22-Apr-2017
    Official Symbol
    Tnfsf12provided by MGI
    Official Full Name
    tumor necrosis factor (ligand) superfamily, member 12provided by MGI
    Primary source
    MGI:MGI:1196259
    See related
    Ensembl:ENSMUSG00000097328 Vega:OTTMUSG00000005999
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dr3l; Apo3l; Dr3lg; Tweak
    Orthologs
    Location:
    11; 11 B3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (69686240..69696098, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69499850..69509499, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene SUMO/sentrin specific peptidase 3 Neighboring gene tumor necrosis factor (ligand) superfamily, member 13, opposite strand Neighboring gene tumor necrosis factor (ligand) superfamily, membrane-bound member 13 Neighboring gene tumor necrosis factor (ligand) superfamily, member 13 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide A Neighboring gene solute carrier family 35, member G3

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Readthrough Tnfsfm13

    Readthrough gene: Tnfsfm13, Included gene: Tnfsf13

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    extrinsic apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    immune response IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of extrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    tumor necrosis factor ligand superfamily member 12
    Names
    TNF-related weak inducer of apoptosis

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011614.3NP_035744.1  tumor necrosis factor ligand superfamily member 12

      See identical proteins and their annotated locations for NP_035744.1

      Status: VALIDATED

      Source sequence(s)
      AL603707
      Consensus CDS
      CCDS24907.1
      UniProtKB/Swiss-Prot
      O54907
      UniProtKB/TrEMBL
      Q5F2A0
      Related
      ENSMUSP00000137972.1, OTTMUSP00000006216, ENSMUST00000181810.7, OTTMUST00000013428
      Conserved Domains (1) summary
      smart00207
      Location:131248
      TNF; Tumour necrosis factor family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      69686240..69696098 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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