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    Baz2a bromodomain adjacent to zinc finger domain, 2A [ Mus musculus (house mouse) ]

    Gene ID: 116848, updated on 14-May-2017
    Official Symbol
    Baz2aprovided by MGI
    Official Full Name
    bromodomain adjacent to zinc finger domain, 2Aprovided by MGI
    Primary source
    MGI:MGI:2151152
    See related
    Ensembl:ENSMUSG00000040054
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tip5; Walp3; C78388; AA415431; mKIAA0314; C030005G16Rik
    Orthologs
    Location:
    10; 10 D3
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (128090629..128129303)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127529839..127566359)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene prostaglandin E synthase 3 Neighboring gene ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit Neighboring gene microRNA 677 Neighboring gene RNA binding motif, single stranded interacting protein 2 Neighboring gene predicted gene 4556

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase I CORE element sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    lysine-acetylated histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromatin remodeling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    chromatin silencing at rDNA IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromatin silencing at rDNA IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    covalent chromatin modification IEA
    Inferred from Electronic Annotation
    more info
     
    heterochromatin assembly involved in chromatin silencing IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heterochromatin assembly involved in chromatin silencing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone H3-K9 methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone H4 deacetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone H4-K20 methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone deacetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase I promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    chromatin silencing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    rDNA heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    bromodomain adjacent to zinc finger domain protein 2A
    Names
    TTF-I-interacting protein 5
    transcription termination factor I-interacting protein 5

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_054078.2NP_473419.2  bromodomain adjacent to zinc finger domain protein 2A

      See identical proteins and their annotated locations for NP_473419.2

      Status: VALIDATED

      Source sequence(s)
      AC131120, AC166817
      Consensus CDS
      CCDS36088.1
      UniProtKB/TrEMBL
      F8VPM0
      Related
      ENSMUSP00000044359.8, ENSMUST00000045621.8
      Conserved Domains (6) summary
      cd05503
      Location:17801876
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:839901
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:541613
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16621708
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:402487
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14231461
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      128090629..128129303
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243281.2XP_011241583.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011241583.1

      UniProtKB/TrEMBL
      E9Q374
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    2. XM_011243278.2XP_011241580.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011241580.1

      UniProtKB/TrEMBL
      E9Q374
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    3. XM_011243283.2XP_011241585.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011241585.1

      UniProtKB/TrEMBL
      E9Q374
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    4. XM_011243285.2XP_011241587.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

      See identical proteins and their annotated locations for XP_011241587.1

      UniProtKB/TrEMBL
      F8VPM0
      Conserved Domains (6) summary
      cd05503
      Location:17801876
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:839901
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:541613
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16621708
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:402487
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14231461
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    5. XM_011243280.2XP_011241582.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011241582.1

      UniProtKB/TrEMBL
      E9Q374
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    6. XM_011243282.2XP_011241584.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011241584.1

      UniProtKB/TrEMBL
      E9Q374
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    7. XM_017313767.1XP_017169256.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      UniProtKB/TrEMBL
      E9Q374
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    8. XM_006513115.2XP_006513178.1  bromodomain adjacent to zinc finger domain protein 2A isoform X3

      Conserved Domains (6) summary
      cd05503
      Location:17801876
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    9. XM_006513114.2XP_006513177.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

      See identical proteins and their annotated locations for XP_006513177.1

      UniProtKB/TrEMBL
      F8VPM0
      Conserved Domains (6) summary
      cd05503
      Location:17801876
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:839901
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:541613
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16621708
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:402487
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14231461
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    10. XM_011243284.2XP_011241586.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011241586.1

      UniProtKB/TrEMBL
      E9Q374
      Related
      ENSMUSP00000129803.2, ENSMUST00000170054.8
      Conserved Domains (6) summary
      cd05503
      Location:17811877
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:840902
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:542614
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16631709
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:273488
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14241462
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    11. XM_011243286.2XP_011241588.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

      See identical proteins and their annotated locations for XP_011241588.1

      UniProtKB/TrEMBL
      F8VPM0
      Related
      ENSMUSP00000151961.1, ENSMUST00000220049.1
      Conserved Domains (6) summary
      cd05503
      Location:17801876
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:839901
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:541613
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:16621708
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam09214
      Location:402487
      Prd1-P2; Bacteriophage Prd1, adsorption protein P2
      pfam15614
      Location:14231461
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    12. XM_011243287.2XP_011241589.1  bromodomain adjacent to zinc finger domain protein 2A isoform X4

      Conserved Domains (5) summary
      cd05503
      Location:12401336
      Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
      smart00571
      Location:299361
      DDT; domain in different transcription and chromosome remodeling factors
      cd01397
      Location:1073
      HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
      cd15629
      Location:11221168
      PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
      pfam15614
      Location:883921
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

    RNA

    1. XR_001779420.1 RNA Sequence

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