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    MLP2 Mlp2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854657, updated on 9-Apr-2017
    Gene symbol
    MLP2
    Gene description
    Mlp2p
    Primary source
    SGD:S000001411
    Locus tag
    YIL149C
    Gene type
    protein coding
    RNA name
    Mlp2p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See MLP2 in Map Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (63028..68067, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Esl1p Neighboring gene Mcm10p Neighboring gene ubiquitin-ribosomal 60S subunit protein L40A fusion protein Neighboring gene Sln1p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • RNA transport, organism-specific biosystem (from KEGG)
      RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • RNA transport, conserved biosystem (from KEGG)
      RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ribonucleoprotein complex binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    ribonucleoprotein complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    colocalizes_with intracellular ribonucleoprotein complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear pore nuclear basket IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with spindle pole body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spindle pole body IEA
    Inferred from Electronic Annotation
    more info
     
    spindle pole body IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Names
    Mlp2p
    NP_012117.3
    • Myosin-like protein associated with the nuclear envelope; nuclear basket protein that connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length; MLP2 has a paralog, MLP1, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      63028..68067 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179497.3NP_012117.3  TPA: Mlp2p [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_012117.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P40457
      Conserved Domains (2) summary
      COG1196
      Location:5911417
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:59988
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
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