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    Anxa7 annexin A7 [ Mus musculus (house mouse) ]

    Gene ID: 11750, updated on 5-Nov-2017
    Official Symbol
    Anxa7provided by MGI
    Official Full Name
    annexin A7provided by MGI
    Primary source
    MGI:MGI:88031
    See related
    Ensembl:ENSMUSG00000021814
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Anx7; synexin; AI265384; AI316497
    Expression
    Ubiquitous expression in placenta adult (RPKM 48.4), bladder adult (RPKM 40.7) and 28 other tissues See more
    Orthologs
    Location:
    14 A3; 14 11.53 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (20455261..20480133, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (21274483..21299355, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene cilia and flagella associated protein 70 Neighboring gene MSS51 mitochondrial translational activator Neighboring gene protein phosphatase 3, catalytic subunit, beta isoform Neighboring gene RIKEN cDNA 1810062O18 gene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    calcium-dependent phospholipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    integrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular water homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hemostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    membrane fusion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell shape IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to calcium ion ISO
    Inferred from Sequence Orthology
    more info
     
    response to organic cyclic compound ISO
    Inferred from Sequence Orthology
    more info
     
    response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with chromaffin granule membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    annexin A7
    Names
    annexin VII
    annexin-7

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110794.1NP_001104264.1  annexin A7

      See identical proteins and their annotated locations for NP_001104264.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate splice site which results in a shorter 5' UTR, as compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK134589, AK169199, CJ163805
      Consensus CDS
      CCDS26845.1
      UniProtKB/Swiss-Prot
      Q07076
      UniProtKB/TrEMBL
      Q3UYL7
      Related
      ENSMUSP00000066035.9, ENSMUST00000065504.16
      Conserved Domains (1) summary
      pfam00191
      Location:164229
      Annexin; Annexin
    2. NM_009674.3NP_033804.2  annexin A7

      See identical proteins and their annotated locations for NP_033804.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK032013, AK134589, AK169199, CJ163805
      Consensus CDS
      CCDS26845.1
      UniProtKB/Swiss-Prot
      Q07076
      UniProtKB/TrEMBL
      Q3UYL7, Q8CCV9
      Related
      ENSMUSP00000153669.1, ENSMUST00000224975.1
      Conserved Domains (1) summary
      pfam00191
      Location:164229
      Annexin; Annexin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      20455261..20480133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518452.2XP_006518515.1  annexin A7 isoform X1

      See identical proteins and their annotated locations for XP_006518515.1

      Related
      ENSMUSP00000098405.5, ENSMUST00000100844.5
      Conserved Domains (1) summary
      pfam00191
      Location:186251
      Annexin; Annexin
    2. XM_006518453.3XP_006518516.1  annexin A7 isoform X1

      See identical proteins and their annotated locations for XP_006518516.1

      Conserved Domains (1) summary
      pfam00191
      Location:186251
      Annexin; Annexin
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