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    Stk17b serine/threonine kinase 17b (apoptosis-inducing) [ Mus musculus (house mouse) ]

    Gene ID: 98267, updated on 6-Feb-2017
    Official Symbol
    Stk17bprovided by MGI
    Official Full Name
    serine/threonine kinase 17b (apoptosis-inducing)provided by MGI
    Primary source
    MGI:MGI:2138162
    See related
    Ensembl:ENSMUSG00000026094 Vega:OTTMUSG00000021434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Drak2; AI120141; 3110009A03Rik
    Orthologs
    Location:
    1; 1 C1.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (53755512..53785215, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (53812356..53842059, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 (zinc transporter), member 10 pseudogene Neighboring gene dynein, axonemal, heavy chain 7A Neighboring gene predicted gene, 32311 Neighboring gene HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 Neighboring gene microRNA 7681 Neighboring gene coiled-coil domain containing 150

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of fibroblast apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    programmed cell death ISO
    Inferred from Sequence Orthology
    more info
     
    protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    serine/threonine-protein kinase 17B
    Names
    DAP kinase-related apoptosis-inducing protein kinase 2
    NP_598571.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133810.3NP_598571.2  serine/threonine-protein kinase 17B

      See identical proteins and their annotated locations for NP_598571.2

      Status: VALIDATED

      Source sequence(s)
      AK165291, AY092028, BY034689
      Consensus CDS
      CCDS14955.1
      UniProtKB/Swiss-Prot
      Q8BG48
      Related
      ENSMUSP00000027263, OTTMUSP00000023815, ENSMUST00000027263, OTTMUST00000050819
      Conserved Domains (2) summary
      smart00220
      Location:37293
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14198
      Location:24293
      STKc_DRAK2; The catalytic domain of the Serine/Threonine Kinase, Death-associated protein kinase-Related Apoptosis-inducing protein Kinase 2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      53755512..53785215 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496359.3XP_006496422.1  serine/threonine-protein kinase 17B isoform X1

      Conserved Domains (2) summary
      smart00220
      Location:3165
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:1165
      PKc_like; Protein Kinases, catalytic domain
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