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    Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [ Mus musculus (house mouse) ]

    Gene ID: 20586, updated on 22-May-2018
    Official Symbol
    Smarca4provided by MGI
    Official Full Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4provided by MGI
    Primary source
    MGI:MGI:88192
    See related
    Ensembl:ENSMUSG00000032187 Vega:OTTMUSG00000037140
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Brg1; BAF190A; SW1/SNF; HP1-BP72; SNF2beta; b2b692Clo; b2b508.1Clo
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 48.7), CNS E14 (RPKM 45.5) and 28 other tissues See more
    Orthologs
    See Smarca4 in Genome Data Viewer
    Location:
    9 A3; 9 7.84 cM
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (21616106..21704230)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21420613..21508674)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene 7904 Neighboring gene microRNA 1946b Neighboring gene predicted gene, 39304 Neighboring gene predicted gene, 26511 Neighboring gene low density lipoprotein receptor

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ATPase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    DNA polymerase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    DNA polymerase binding ISO
    Inferred from Sequence Orthology
    more info
     
    DNA-dependent ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase I CORE element sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II proximal promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Tat protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    androgen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    histone binding IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity, acting on acid anhydrides IEA
    Inferred from Electronic Annotation
    more info
     
    lysine-acetylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    p53 binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ATP-dependent chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    DNA methylation on cytosine within a CG sequence IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    aorta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    aortic smooth muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blastocyst growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blastocyst hatching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    coronary vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    definitive erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic hindlimb morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epidermis morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    extracellular matrix organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    forebrain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glial cell fate determination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart trabecula formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    hindbrain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone H3 acetylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    keratinocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lens fiber cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    liver development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    methylation-dependent chromatin silencing IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of androgen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neurogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleosome assembly TAS
    Traceable Author Statement
    more info
    PubMed 
    nucleosome disassembly ISO
    Inferred from Sequence Orthology
    more info
     
    outflow tract morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pharyngeal arch artery morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation by host of viral transcription ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of DNA binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of DNA binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of glucose mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of pri-miRNA transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    vasculogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ventricular septum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SWI/SNF complex ISO
    Inferred from Sequence Orthology
    more info
     
    SWI/SNF complex TAS
    Traceable Author Statement
    more info
    PubMed 
    heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nBAF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    npBAF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    npBAF complex ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear euchromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perichromatin fibrils IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    transcription activator BRG1
    Names
    ATP-dependent helicase SMARCA4
    BRG1-associated factor 190A
    SNF2-beta
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
    protein brahma homolog 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001174078.1NP_001167549.1  transcription activator BRG1 isoform 1

      See identical proteins and their annotated locations for NP_001167549.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an alternate in-frame exon and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 4.
      Source sequence(s)
      AK160825, BC079560
      Consensus CDS
      CCDS52737.1
      UniProtKB/Swiss-Prot
      Q3TKT4
      UniProtKB/TrEMBL
      A0A0R4J170
      Related
      ENSMUSP00000096547.3, ENSMUST00000098948.9
      Conserved Domains (8) summary
      cd05516
      Location:14281534
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:12891356
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    2. NM_001174079.1NP_001167550.1  transcription activator BRG1 isoform 3

      See identical proteins and their annotated locations for NP_001167550.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 4.
      Source sequence(s)
      AK160825, AK166837, BC079560
      Consensus CDS
      CCDS57662.1
      UniProtKB/Swiss-Prot
      Q3TKT4
      Related
      ENSMUSP00000133922.1, OTTMUSP00000053361, ENSMUST00000174008.7, OTTMUST00000095629
      Conserved Domains (8) summary
      cd05516
      Location:14251530
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:12891356
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    3. NM_001357764.1NP_001344693.1  transcription activator BRG1 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (4).
      Source sequence(s)
      AC161371
      Conserved Domains (8) summary
      cd05516
      Location:14581564
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    4. NM_011417.3NP_035547.2  transcription activator BRG1 isoform 2

      See identical proteins and their annotated locations for NP_035547.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 4. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 4..
      Source sequence(s)
      AK160825, BC079560
      Consensus CDS
      CCDS22909.1
      UniProtKB/Swiss-Prot
      Q3TKT4
      Related
      ENSMUSP00000034707.8, OTTMUSP00000053360, ENSMUST00000034707.14, OTTMUST00000095628
      Conserved Domains (8) summary
      cd05516
      Location:14251531
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:12891356
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      21616106..21704230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242434.1XP_011240736.1  transcription activator BRG1 isoform X1

      See identical proteins and their annotated locations for XP_011240736.1

      Conserved Domains (9) summary
      cd05516
      Location:14611567
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:774913
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam08430
      Location:43164
      Forkhead_N; Forkhead N-terminal region
      pfam00176
      Location:7571052
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:10791194
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
    2. XM_011242435.1XP_011240737.1  transcription activator BRG1 isoform X2

      Conserved Domains (9) summary
      cd05516
      Location:14611566
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:774913
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam08430
      Location:54164
      Forkhead_N; Forkhead N-terminal region
      pfam00176
      Location:7571052
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:10791194
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
    3. XM_006510122.2XP_006510185.2  transcription activator BRG1 isoform X3

      See identical proteins and their annotated locations for XP_006510185.2

      Conserved Domains (8) summary
      cd05516
      Location:14581564
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    4. XM_011242436.1XP_011240738.1  transcription activator BRG1 isoform X4

      Conserved Domains (9) summary
      cd05516
      Location:14581563
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:774913
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam08430
      Location:43164
      Forkhead_N; Forkhead N-terminal region
      pfam00176
      Location:7571052
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:10791194
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
    5. XM_006510117.2XP_006510180.2  transcription activator BRG1 isoform X6

      See identical proteins and their annotated locations for XP_006510180.2

      UniProtKB/Swiss-Prot
      Q3TKT4
      UniProtKB/TrEMBL
      A0A0R4J170
      Conserved Domains (8) summary
      cd05516
      Location:14281534
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:12891356
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    6. XM_006510119.2XP_006510182.2  transcription activator BRG1 isoform X7

      See identical proteins and their annotated locations for XP_006510182.2

      UniProtKB/Swiss-Prot
      Q3TKT4
      Conserved Domains (8) summary
      cd05516
      Location:14251531
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:12891356
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    7. XM_006510120.2XP_006510183.2  transcription activator BRG1 isoform X8

      See identical proteins and their annotated locations for XP_006510183.2

      UniProtKB/Swiss-Prot
      Q3TKT4
      Conserved Domains (8) summary
      cd05516
      Location:14251530
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:12891356
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    8. XM_011242438.1XP_011240740.1  transcription activator BRG1 isoform X1

      See identical proteins and their annotated locations for XP_011240740.1

      Conserved Domains (9) summary
      cd05516
      Location:14611567
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:774913
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam08430
      Location:43164
      Forkhead_N; Forkhead N-terminal region
      pfam00176
      Location:7571052
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:10791194
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
    9. XM_017313233.1XP_017168722.1  transcription activator BRG1 isoform X9

    10. XM_017313234.1XP_017168723.1  transcription activator BRG1 isoform X10

    11. XM_017313235.1XP_017168724.1  transcription activator BRG1 isoform X11

    12. XM_017313232.1XP_017168721.1  transcription activator BRG1 isoform X3

      Conserved Domains (8) summary
      cd05516
      Location:14581564
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:612656
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:460532
      HSA; domain in helicases and associated with SANT domains
      pfam08880
      Location:171205
      QLQ; QLQ
      pfam09606
      Location:42217
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam14619
      Location:13221389
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl25732
      Location:370570
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26465
      Location:7501232
      SNF2_N; SNF2 family N-terminal domain
    13. XM_011242437.2XP_011240739.1  transcription activator BRG1 isoform X5

      Conserved Domains (9) summary
      cd05516
      Location:14811587
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:632676
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:480552
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:794933
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam08430
      Location:63184
      Forkhead_N; Forkhead N-terminal region
      pfam00176
      Location:7771072
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:10991214
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:191225
      QLQ; QLQ
      pfam14619
      Location:13421409
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
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