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    SPT2 Spt2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856908, updated on 5-Nov-2017
    Gene symbol
    SPT2
    Gene description
    Spt2p
    Primary source
    SGD:S000000963
    Locus tag
    YER161C
    Gene type
    protein coding
    RNA name
    Spt2p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    EXA1; SIN1
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (499347..500348, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene gag-pol fusion protein Neighboring gene gag protein Neighboring gene Rad4p Neighboring gene gamma-glutamylcyclotransferase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA secondary structure binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    RNA polyadenylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    RNA polyadenylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription elongation from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Spt2p
    NP_011088.1
    • Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components; relocalizes to the cytosol in response to hypoxia; similar to mammalian HMG1 proteins

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      499347..500348 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179051.1NP_011088.1  TPA: Spt2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011088.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P06843
      Conserved Domains (1) summary
      pfam08243
      Location:218330
      SPT2; SPT2 chromatin protein
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