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    MCM10 Mcm10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854656, updated on 5-Nov-2017
    Gene symbol
    MCM10
    Gene description
    Mcm10p
    Primary source
    SGD:S000001412
    Locus tag
    YIL150C
    Gene type
    protein coding
    RNA name
    Mcm10p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    DNA43
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (61013..62728, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Esl1p Neighboring gene Mlp2p Neighboring gene ubiquitin-ribosomal 60S subunit protein L40A fusion protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA replication origin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication initiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    DNA replication initiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    DNA strand elongation involved in DNA replication IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    DNA strand elongation involved in DNA replication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin silencing at silent mating-type cassette IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin silencing at telomere IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    double-strand break repair via break-induced replication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    replication fork IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    replication fork protection complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    Mcm10p
    NP_012116.1
    • Essential chromatin-associated protein; involved in initiation of DNA replication; required for association of MCM2-7 complex with replication origins; required to stabilize catalytic subunit of DNA polymerase-alpha; self-associates through its N-terminal domain

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      61013..62728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179498.1NP_012116.1  TPA: Mcm10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012116.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P32354
      Conserved Domains (1) summary
      pfam09329
      Location:301347
      zf-primase; Primase zinc finger
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