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    Snai1 snail family zinc finger 1 [ Mus musculus (house mouse) ]

    Gene ID: 20613, updated on 15-May-2018
    Official Symbol
    Snai1provided by MGI
    Official Full Name
    snail family zinc finger 1provided by MGI
    Primary source
    MGI:MGI:98330
    See related
    Ensembl:ENSMUSG00000042821 Vega:OTTMUSG00000001149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sna; Sna1; Snail; Snail1
    Expression
    Broad expression in limb E14.5 (RPKM 49.3), lung adult (RPKM 33.6) and 20 other tissues See more
    Orthologs
    See Snai1 in Genome Data Viewer
    Location:
    2 H3; 2 87.33 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (167538195..167542814)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (167363727..167368314)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 2 Neighboring gene ring finger protein 114 Neighboring gene cytochrome b-c1 complex subunit 6, mitochondrial-like Neighboring gene predicted gene 11476 Neighboring gene predicted gene, 31619 Neighboring gene ribosomal protein L18 pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    Notch signaling involved in heart development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cartilage morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    epithelial to mesenchymal transition IDA
    Inferred from Direct Assay
    more info
    PubMed 
    epithelial to mesenchymal transition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    epithelial to mesenchymal transition involved in endocardial cushion formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    hair follicle morphogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heterochromatin organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    left/right pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mesoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mesoderm formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of DNA damage response, signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell differentiation involved in embryonic placenta development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of vitamin D biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial to mesenchymal transition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of bicellular tight junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    roof of mouth development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    trophoblast giant cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pericentric heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    zinc finger protein SNAI1
    Names
    snail homolog 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011427.3NP_035557.1  zinc finger protein SNAI1

      See identical proteins and their annotated locations for NP_035557.1

      Status: VALIDATED

      Source sequence(s)
      AK144478, AL589870, BU756566
      Consensus CDS
      CCDS17102.1
      UniProtKB/Swiss-Prot
      Q02085
      UniProtKB/TrEMBL
      Q4FK48
      Related
      ENSMUSP00000050581.7, OTTMUSP00000001090, ENSMUST00000052631.7, OTTMUST00000002241
      Conserved Domains (4) summary
      COG5048
      Location:177253
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:182202
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:208230
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:195218
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      167538195..167542814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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