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    gpa-16 G Protein, Alpha subunit [ Caenorhabditis elegans ]

    Gene ID: 171675, updated on 7-Sep-2017
    Gene symbol
    gpa-16
    Gene description
    G Protein, Alpha subunit
    Primary source
    WormBase:WBGene00001678
    Locus tag
    CELE_Y95B8A.5
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See gpa-16 in Map Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (897290..905853)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene High Incidence of Males (increased X chromosome loss) Neighboring gene ncRNA Neighboring gene hypothetical protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    G-protein beta/gamma-subunit complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    G-protein coupled receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    GDP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    guanyl nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signal transducer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    adenylate cyclase-modulating G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    embryonic axis specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment of mitotic spindle orientation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    heterotrimeric G-protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Names
    G Protein, Alpha subunit
    Guanine nucleotide-binding protein alpha-16 subunit
    NP_001293186.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class gpa
    NP_001293187.1
    • Partially confirmed by transcript evidence;
      Product from WormBase gene class gpa
    NP_490790.1
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      897290..905853
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058389.3NP_490790.1  Guanine nucleotide-binding protein alpha-16 subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490790.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9N2V6
      Conserved Domains (2) summary
      cd00066
      Location:34351
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
      smart00275
      Location:13355
      G_alpha; G protein alpha subunit
    2. NM_001306257.1NP_001293186.1  G Protein, Alpha subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293186.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CK09
      Conserved Domains (1) summary
      cl21455
      Location:1120
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    3. NM_001306258.1NP_001293187.1  G Protein, Alpha subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293187.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLF2
      Conserved Domains (1) summary
      cl21455
      Location:1109
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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