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    Nbl1 neuroblastoma, suppression of tumorigenicity 1 [ Mus musculus (house mouse) ]

    Gene ID: 17965, updated on 22-Oct-2017
    Official Symbol
    Nbl1provided by MGI
    Official Full Name
    neuroblastoma, suppression of tumorigenicity 1provided by MGI
    Primary source
    MGI:MGI:104591
    See related
    Ensembl:ENSMUSG00000041120 Vega:OTTMUSG00000009896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DAN; NO3; Dana; D4H1S1733E
    Expression
    Broad expression in ovary adult (RPKM 159.8), lung adult (RPKM 140.6) and 20 other tissues See more
    Location:
    4 70.57 cM; 4 D3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (139082291..139092980, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (138638207..138648885, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene transmembrane and coiled-coil domains 4 Neighboring gene predicted gene, 33214 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 6 Neighboring gene predicted gene 45533 Neighboring gene mitochondrial inner membrane organizing system 1 Neighboring gene predicted gene, 33304 Neighboring gene heat shock protein 1 (chaperonin 10), pseudogene 4

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • TGF-beta signaling pathway, organism-specific biosystem (from KEGG)
      TGF-beta signaling pathway, organism-specific biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
    • TGF-beta signaling pathway, conserved biosystem (from KEGG)
      TGF-beta signaling pathway, conserved biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...

    Markers

    Homology

    Clone Names

    • MGC123430

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    BMP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    morphogen activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    neuroblastoma suppressor of tumorigenicity 1
    Names
    N03
    zinc finger protein DAN

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008675.2NP_032701.2  neuroblastoma suppressor of tumorigenicity 1 precursor

      See identical proteins and their annotated locations for NP_032701.2

      Status: VALIDATED

      Source sequence(s)
      AK146535
      Consensus CDS
      CCDS18839.1
      UniProtKB/Swiss-Prot
      Q61477
      Related
      ENSMUSP00000045608.6, OTTMUSP00000010476, ENSMUST00000042844.6, OTTMUST00000022949
      Conserved Domains (1) summary
      cl21545
      Location:22120
      GHB_like; Glycoprotein hormone beta chain homologues

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      139082291..139092980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538625.3XP_006538688.1  neuroblastoma suppressor of tumorigenicity 1 isoform X1

      See identical proteins and their annotated locations for XP_006538688.1

      UniProtKB/Swiss-Prot
      Q61477
      Conserved Domains (1) summary
      cl21545
      Location:22120
      GHB_like; Glycoprotein hormone beta chain homologues
    2. XM_006538626.3XP_006538689.1  neuroblastoma suppressor of tumorigenicity 1 isoform X1

      See identical proteins and their annotated locations for XP_006538689.1

      UniProtKB/Swiss-Prot
      Q61477
      Conserved Domains (1) summary
      cl21545
      Location:22120
      GHB_like; Glycoprotein hormone beta chain homologues
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