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    Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 57376, updated on 5-Nov-2017
    Official Symbol
    Smarce1provided by MGI
    Official Full Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1provided by MGI
    Primary source
    MGI:MGI:1927347
    See related
    Ensembl:ENSMUSG00000037935 Vega:OTTMUSG00000006455
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Baf27; 2810417B20Rik; 5830412H02Rik; 9030408N19Rik
    Orthologs
    Location:
    11; 11 D
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (99209047..99231339, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (99070361..99092331, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene chemokine (C-C motif) receptor 7 Neighboring gene predicted gene, 32249 Neighboring gene keratin 222 Neighboring gene predicted gene, 32385 Neighboring gene keratin 24

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to RNA polymerase II proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    ligand-dependent nuclear receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to nucleosomal DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    ATP-dependent chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    covalent chromatin modification IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    neurogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    nucleosome disassembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SWI/SNF complex ISO
    Inferred from Sequence Orthology
    more info
     
    SWI/SNF superfamily-type complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nBAF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    npBAF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    transcriptional repressor complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
    Names
    BAF57
    BRG1-associated factor 57
    SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020618.4NP_065643.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

      See identical proteins and their annotated locations for NP_065643.1

      Status: VALIDATED

      Source sequence(s)
      BC065043, CN710586
      Consensus CDS
      CCDS25374.1
      UniProtKB/Swiss-Prot
      O54941
      Related
      ENSMUSP00000099422.3, OTTMUSP00000006855, ENSMUST00000103133.3, OTTMUST00000014750
      Conserved Domains (1) summary
      cd01390
      Location:70131
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      99209047..99231339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533828.2XP_006533891.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X2

      See identical proteins and their annotated locations for XP_006533891.1

      Conserved Domains (1) summary
      cd01390
      Location:261
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    2. XM_011249158.1XP_011247460.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X2

      See identical proteins and their annotated locations for XP_011247460.1

      Conserved Domains (1) summary
      cd01390
      Location:261
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    3. XM_006533827.3XP_006533890.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1

      Conserved Domains (1) summary
      cd01390
      Location:3596
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
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