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    ADD1 adducin 1 [ Homo sapiens (human) ]

    Gene ID: 118, updated on 23-Sep-2017
    Official Symbol
    ADD1provided by HGNC
    Official Full Name
    adducin 1provided by HGNC
    Primary source
    HGNC:HGNC:243
    See related
    Ensembl:ENSG00000087274 MIM:102680; Vega:OTTHUMG00000122080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ADDA
    Summary
    Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
    Orthologs
    Location:
    4p16.3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 4 NC_000004.12 (2843732..2930076)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (2845454..2931803)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102723763 Neighboring gene SH3 domain binding protein 2 Neighboring gene NOP14 antisense RNA 1 Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene NOP14 nucleolar protein

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Apoptosis, organism-specific biosystem (from REACTOME)
      Apoptosis, organism-specific biosystemApoptosis is a distinct form of cell death that is functionally and morphologically different from necrosis. Nuclear chromatin condensation, cytoplasmic shrinking, dilated endoplasmic reticulum, and ...
    • Apoptotic cleavage of cellular proteins, organism-specific biosystem (from REACTOME)
      Apoptotic cleavage of cellular proteins, organism-specific biosystemApoptotic cell death is achieved by the caspase-mediatedcleavage of various vital proteins. Among caspase targets are proteins such as E-cadherin, Beta-catenin, alpha fodrin, GAS2, FADK, alpha adduc...
    • Apoptotic execution phase, organism-specific biosystem (from REACTOME)
      Apoptotic execution phase, organism-specific biosystemIn the execution phase of apoptosis, effector caspases cleave vital cellular proteins leading to the morphological changes that characterize apoptosis. These changes include destruction of the nucle...
    • Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem (from REACTOME)
      Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystemCaspase-mediated cleavage of a number of proteins in the cortical actin network ( ) microfilament system and others involved in maintenance of the cytoskeletal architecture (vimentin, or Gas2 and ...
    • IRE1alpha activates chaperones, organism-specific biosystem (from REACTOME)
      IRE1alpha activates chaperones, organism-specific biosystemIRE1-alpha is a single-pass transmembrane protein that resides in the endoplasmic reticulum (ER) membrane. The C-terminus of IRE1-alpha is located in the cytosol; the N-terminus is located in the ER ...
    • Metabolism of proteins, organism-specific biosystem (from REACTOME)
      Metabolism of proteins, organism-specific biosystemProtein metabolism comprises the pathways of translation, post-translational modification and protein folding.
    • Miscellaneous transport and binding events, organism-specific biosystem (from REACTOME)
      Miscellaneous transport and binding events, organism-specific biosystemThis section contains known transport and binding events that as of yet cannot be placed in exisiting pathways (Purves 2001, He et al. 2009, Rees et al. 2009).
    • Programmed Cell Death, organism-specific biosystem (from REACTOME)
      Programmed Cell Death, organism-specific biosystemCell death is a fundamental cellular response that has a crucial role in shaping our bodies during development and in regulating tissue homeostasis by eliminating unwanted cells. There are a number o...
    • Transmembrane transport of small molecules, organism-specific biosystem (from REACTOME)
      Transmembrane transport of small molecules, organism-specific biosystem
      Transmembrane transport of small molecules
    • Unfolded Protein Response (UPR), organism-specific biosystem (from REACTOME)
      Unfolded Protein Response (UPR), organism-specific biosystemThe Unfolded Protein Response (UPR) is a regulatory system that protects the Endoplasmic Reticulum (ER) from overload. The UPR is provoked by the accumulation of improperly folded protein in the ER d...
    • XBP1(S) activates chaperone genes, organism-specific biosystem (from REACTOME)
      XBP1(S) activates chaperone genes, organism-specific biosystemXbp-1 (S) binds the sequence CCACG in ER Stress Responsive Elements (ERSE, consensus sequence CCAAT (N)9 CCACG) located upstream from many genes. The ubiquitous transcription factor NF-Y, a heterotri...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC3339, MGC44427

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin binding TAS
    Traceable Author Statement
    more info
    PubMed 
    actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cadherin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    spectrin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    IRE1-mediated unfolded protein response TAS
    Traceable Author Statement
    more info
     
    actin cytoskeleton organization IC
    Inferred by Curator
    more info
    PubMed 
    actin filament bundle assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    barbed-end actin filament capping IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to calcium ion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    erythrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    hemoglobin metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    homeostasis of number of cells within a tissue IEA
    Inferred from Electronic Annotation
    more info
     
    in utero embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism growth IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of adherens junction organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of establishment of endothelial barrier IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transmembrane transport TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    F-actin capping protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell adherens junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol TAS
    Traceable Author Statement
    more info
     
    focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear body IDA
    Inferred from Direct Assay
    more info
     
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
     
    colocalizes_with plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    alpha-adducin
    Names
    adducin 1 (alpha)
    erythrocyte adducin alpha subunit

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_012037.1 RefSeqGene

      Range
      5001..91220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001119.4NP_001110.2  alpha-adducin isoform a

      See identical proteins and their annotated locations for NP_001110.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) utilizes an in-frame alternate splice site in the coding region, compared to variant 2. This results in a shorter protein (isoform a), compared to isoform b. Variants 1, 6, and 7 all encode the same isoform (a).
      Source sequence(s)
      BI460192, BU729599, CR995783, CX783962, X58141
      Consensus CDS
      CCDS43205.1
      UniProtKB/Swiss-Prot
      P35611
      Related
      ENSP00000381197.1, OTTHUMP00000151164, ENST00000398129.5, OTTHUMT00000242840
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:584702
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    2. NM_001286645.1NP_001273574.1  alpha-adducin isoform e

      See identical proteins and their annotated locations for NP_001273574.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and contains two additional alternate exons compared to variant 1. The resulting isoform (e) has an alternate in-frame segment and a shorter and distinct C-terminus compared to isoform a. Variants 5 and 11 both encode the same isoform (e).
      Source sequence(s)
      BC042998, BU729599
      Consensus CDS
      CCDS75094.1
      UniProtKB/Swiss-Prot
      P35611
      Related
      ENSP00000348100.3, OTTHUMP00000151163, ENST00000355842.7, OTTHUMT00000242839
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    3. NM_001354754.1NP_001341683.1  alpha-adducin isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6), as well as variants 1 and 7, encodes isoform a.
      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:584702
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    4. NM_001354755.1NP_001341684.1  alpha-adducin isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7), as well as variants 1 and 6, encodes isoform a.
      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:584702
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    5. NM_001354756.1NP_001341685.1  alpha-adducin isoform f

      Status: REVIEWED

      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl27087
      Location:624725
      SPOR; Sporulation related domain
    6. NM_001354757.1NP_001341686.1  alpha-adducin isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variants 3 and 10, encodes isoform c.
      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    7. NM_001354758.1NP_001341687.1  alpha-adducin isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 3 and 9, encodes isoform c.
      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    8. NM_001354759.1NP_001341688.1  alpha-adducin isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variant 5, encodes isoform e.
      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    9. NM_001354761.1NP_001341690.1  alpha-adducin isoform g

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) encodes the longest isoform (g).
      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:646764
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    10. NM_001354762.1NP_001341691.1  alpha-adducin isoform h

      Status: REVIEWED

      Source sequence(s)
      AL121750, AL390065, BX465861
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    11. NM_014189.3NP_054908.2  alpha-adducin isoform b

      See identical proteins and their annotated locations for NP_054908.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) encodes isoform b.
      Source sequence(s)
      BI460192, BU729599, CA391117, CR995783, CX783962, X58141
      Consensus CDS
      CCDS3363.1
      UniProtKB/Swiss-Prot
      P35611
      Related
      ENSP00000264758.6, ENST00000264758.11
      Conserved Domains (2) summary
      pfam05466
      Location:615733
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    12. NM_014190.3NP_054909.2  alpha-adducin isoform c

      See identical proteins and their annotated locations for NP_054909.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) includes an additional exon in the 3' coding region, which results in a frameshift, compared to variant 2. The encoded protein (isoform c) contains an early stop codon and shorter C-terminus, compared to isoform b. Variants 3, 9, and 10 all encode the same isoform (c).
      Source sequence(s)
      BC042998, BI460192, BU729599, CR995783, X58141
      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    13. NM_176801.2NP_789771.1  alpha-adducin isoform d

      See identical proteins and their annotated locations for NP_789771.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) utilizes an alternate splice site and includes an additional exon in the coding region, which results in a frameshift, compared to variant 2. The encoded protein (isoform d) contains an early stop codon and shorter C-terminus, compared to isoform b.
      Source sequence(s)
      BC042998, BI460192, BU729599, CA391117, CR995783, X58141
      Consensus CDS
      CCDS3364.1
      UniProtKB/Swiss-Prot
      P35611
      Related
      ENSP00000381193.1, ENST00000398125.5
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p7 Primary Assembly

      Range
      2843732..2930076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005247936.2XP_005247993.1  alpha-adducin isoform X5

      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    2. XM_005247933.2XP_005247990.1  alpha-adducin isoform X1

      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:646764
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    3. XM_017007708.1XP_016863197.1  alpha-adducin isoform X6

      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    4. XM_005247935.2XP_005247992.1  alpha-adducin isoform X2

      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl27087
      Location:624725
      SPOR; Sporulation related domain
    5. XM_005247937.2XP_005247994.1  alpha-adducin isoform X7

      See identical proteins and their annotated locations for XP_005247994.1

      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    6. XM_017007703.1XP_016863192.1  alpha-adducin isoform X1

      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:646764
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    7. XM_017007710.1XP_016863199.1  alpha-adducin isoform X8

      UniProtKB/Swiss-Prot
      P35611
      Related
      ENSP00000421907.2, OTTHUMP00000218665, ENST00000513328.6, OTTHUMT00000361591
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    8. XM_017007707.1XP_016863196.1  alpha-adducin isoform X4

      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:584702
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    9. XM_005247934.2XP_005247991.1  alpha-adducin isoform X1

      See identical proteins and their annotated locations for XP_005247991.1

      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:646764
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
    10. XM_017007704.1XP_016863193.1  alpha-adducin isoform X3

      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (2) summary
      pfam05466
      Location:615733
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    11. XM_017007709.1XP_016863198.1  alpha-adducin isoform X8

      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (1) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    12. XM_017007705.1XP_016863194.1  alpha-adducin isoform X2

      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl27087
      Location:624725
      SPOR; Sporulation related domain
    13. XM_017007706.1XP_016863195.1  alpha-adducin isoform X4

      UniProtKB/Swiss-Prot
      P35611
      Conserved Domains (2) summary
      cl00214
      Location:145391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
      cl25756
      Location:584702
      BASP1; Brain acid soluble protein 1 (BASP1 protein)

    Alternate CHM1_1.1

    Genomic

    1. NC_018915.2 Alternate CHM1_1.1

      Range
      2843557..2929744
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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