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    Gas8 growth arrest specific 8 [ Mus musculus (house mouse) ]

    Gene ID: 104346, updated on 23-Apr-2017
    Official Symbol
    Gas8provided by MGI
    Official Full Name
    growth arrest specific 8provided by MGI
    Primary source
    MGI:MGI:1202386
    See related
    Ensembl:ENSMUSG00000040220 Vega:OTTMUSG00000061978
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gas11
    Orthologs
    Location:
    8; 8 E1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (123518835..123536657)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (126042735..126060550)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene AFG3-like AAA ATPase 1 Neighboring gene dysbindin (dystrobrevin binding protein 1) domain containing 1 Neighboring gene nuclear encoded rRNA 5S 100 Neighboring gene nuclear encoded rRNA 5S 103

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1)  1 citation

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Rab GTPase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    axoneme assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    brain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell motility IEA
    Inferred from Electronic Annotation
    more info
     
    cellular protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cilium movement involved in cell motility ISO
    Inferred from Sequence Orthology
    more info
     
    determination of left/right symmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epithelial cilium movement IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    flagellated sperm motility IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    regulation of microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    9+2 motile cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axoneme ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    ciliary basal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cilium ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    motile cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    sperm flagellum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    growth arrest-specific protein 8
    Names
    GAS-11
    GAS-8
    beta growth arrest specific protein 11
    growth arrest specific 11
    growth arrest specific protein 11

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018855.2NP_061343.2  growth arrest-specific protein 8

      See identical proteins and their annotated locations for NP_061343.2

      Status: VALIDATED

      Source sequence(s)
      AC158362, AY692443
      Consensus CDS
      CCDS40512.1
      UniProtKB/Swiss-Prot
      Q60779
      UniProtKB/TrEMBL
      Q49MD7
      Related
      ENSMUSP00000090730.5, OTTMUSP00000078483, ENSMUST00000093043.6, OTTMUST00000151324
      Conserved Domains (1) summary
      pfam13851
      Location:221420
      GAS; Growth-arrest specific micro-tubule binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      123518835..123536657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248259.2XP_011246561.1  growth arrest-specific protein 8 isoform X1

      Conserved Domains (1) summary
      pfam13851
      Location:221337
      GAS; Growth-arrest specific micro-tubule binding
    2. XM_006530551.1XP_006530614.1  growth arrest-specific protein 8 isoform X2

      Conserved Domains (1) summary
      pfam13851
      Location:42241
      GAS; Growth-arrest specific micro-tubule binding
    3. XM_006530552.1XP_006530615.1  growth arrest-specific protein 8 isoform X3

      Conserved Domains (1) summary
      pfam13851
      Location:29228
      GAS; Growth-arrest specific micro-tubule binding

    RNA

    1. XR_001778390.1 RNA Sequence

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