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    Rbm6 RNA binding motif protein 6 [ Mus musculus (house mouse) ]

    Gene ID: 19654, updated on 25-May-2017
    Official Symbol
    Rbm6provided by MGI
    Official Full Name
    RNA binding motif protein 6provided by MGI
    Primary source
    MGI:MGI:1338037
    See related
    Ensembl:ENSMUSG00000032582 Vega:OTTMUSG00000043552
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    g16; Def-3; NY-LU-12; mKIAA4015; 4930506F14Rik
    Orthologs
    Location:
    9; 9 F1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (107773559..107872822, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (107675890..107775150, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34605 Neighboring gene RNA binding motif protein 5 Neighboring gene MON1 homolog A, secretory traffciking associated Neighboring gene macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

    Markers

    Homology

    Clone Names

    • KIAA4015

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011251.3NP_035381.2  RNA-binding protein 6 isoform a

      See identical proteins and their annotated locations for NP_035381.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript yet it encodes the longer protein (isoform a).
      Source sequence(s)
      AK145612, BY380685, CJ155377
      Consensus CDS
      CCDS59749.1
      UniProtKB/TrEMBL
      Q3ULB0, S4R1W5
      Related
      ENSMUSP00000138400.1, OTTMUSP00000063802, ENSMUST00000183032.7, OTTMUST00000114305
      Conserved Domains (5) summary
      COG1357
      Location:144259
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cd12314
      Location:456533
      RRM1_RBM6; RNA recognition motif 1 in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:651737
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      cd16163
      Location:763828
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      cl02611
      Location:10461079
      G-patch; G-patch domain
    2. NM_029169.3NP_083445.1  RNA-binding protein 6 isoform b

      See identical proteins and their annotated locations for NP_083445.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different splice site in the 5' end and uses a downstream start codon, compared to variant 1. Isoform b has a shorter N-terminus, compared to isoform a.
      Source sequence(s)
      AK145612, BY380685, CJ155377
      Consensus CDS
      CCDS23507.1
      UniProtKB/TrEMBL
      Q3ULB0
      Related
      ENSMUSP00000035201.5, OTTMUSP00000063801, ENSMUST00000035201.12, OTTMUST00000114304
      Conserved Domains (5) summary
      COG1357
      Location:12127
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cd12314
      Location:324401
      RRM1_RBM6; RNA recognition motif 1 in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:519605
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:914947
      G-patch; G-patch domain
      cd16163
      Location:631696
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      107773559..107872822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313217.1XP_017168706.1  RNA-binding protein 6 isoform X4

      Conserved Domains (3) summary
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
    2. XM_017313216.1XP_017168705.1  RNA-binding protein 6 isoform X2

      UniProtKB/TrEMBL
      Q3ULB0
      Conserved Domains (5) summary
      COG1357
      Location:12127
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cd12314
      Location:324401
      RRM1_RBM6; RNA recognition motif 1 in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:519605
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:914947
      G-patch; G-patch domain
      cd16163
      Location:631696
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
    3. XM_006511651.3XP_006511714.1  RNA-binding protein 6 isoform X4

      See identical proteins and their annotated locations for XP_006511714.1

      Conserved Domains (3) summary
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
    4. XM_006511650.3XP_006511713.1  RNA-binding protein 6 isoform X1

      See identical proteins and their annotated locations for XP_006511713.1

      UniProtKB/TrEMBL
      S4R1W5
      Conserved Domains (5) summary
      COG1357
      Location:144259
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cd12314
      Location:456533
      RRM1_RBM6; RNA recognition motif 1 in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:651737
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      cd16163
      Location:763828
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      cl02611
      Location:10461079
      G-patch; G-patch domain
    5. XM_011242859.2XP_011241161.1  RNA-binding protein 6 isoform X3

      Conserved Domains (4) summary
      cd12563
      Location:166252
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:561594
      G-patch; G-patch domain
      cd16163
      Location:278343
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      cl17169
      Location:1048
      RRM_SF; RNA recognition motif (RRM) superfamily
    6. XM_011242860.2XP_011241162.1  RNA-binding protein 6 isoform X4

      See identical proteins and their annotated locations for XP_011241162.1

      Conserved Domains (3) summary
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
    7. XM_006511653.2XP_006511716.1  RNA-binding protein 6 isoform X4

      See identical proteins and their annotated locations for XP_006511716.1

      Conserved Domains (3) summary
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
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