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    Camk2g calcium/calmodulin-dependent protein kinase II gamma [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171140, updated on 9-Apr-2017
    Official Symbol
    Camk2gprovided by RGD
    Official Full Name
    calcium/calmodulin-dependent protein kinase II gammaprovided by RGD
    Primary source
    RGD:621802
    See related
    Ensembl:ENSRNOG00000009783
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    gamma chain of the CaM kinase II; involved in regulation of potassium currents, particularly in response to oxidative stress [RGD, Feb 2006]
    Location:
    15p16
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (3936721..3995740)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 15 NC_005114.3 (3669219..3724735)

    Chromosome 15 - NC_005114.4Genomic Context describing neighboring genes Neighboring gene N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 Neighboring gene zinc finger SWIM domain-containing protein 8-like Neighboring gene N-deacetylase and N-sulfotransferase 2 Neighboring gene zinc finger, SWIM-type containing 8 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin-dependent protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptidyl-threonine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein autophosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein oligomerization IEA
    Inferred from Electronic Annotation
    more info
     
    protein oligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of long-term neuronal synaptic plasticity TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of relaxation of cardiac muscle IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of relaxation of cardiac muscle ISO
    Inferred from Sequence Orthology
    more info
     
    response to hypoxia IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    sarcoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit gamma
    Names
    caM kinase II subunit gamma
    caM-kinase II gamma chain
    caMK-II subunit gamma
    calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
    calcium/calmodulin-dependent protein kinase type II gamma chain
    NP_598289.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133605.1NP_598289.1  calcium/calmodulin-dependent protein kinase type II subunit gamma

      See identical proteins and their annotated locations for NP_598289.1

      Status: PROVISIONAL

      Source sequence(s)
      J04063
      UniProtKB/Swiss-Prot
      P11730
      Related
      ENSRNOP00000062321.3, ENSRNOT00000066163.4
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:395522
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005114.4 Reference Rnor_6.0 Primary Assembly

      Range
      3936721..3995740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008770487.2XP_008768709.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

      See identical proteins and their annotated locations for XP_008768709.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:456583
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    2. XM_008770486.2XP_008768708.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

      See identical proteins and their annotated locations for XP_008768708.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:456583
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    3. XM_008770488.2XP_008768710.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X2

      See identical proteins and their annotated locations for XP_008768710.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:445572
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    4. XM_008770490.2XP_008768712.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X4

      See identical proteins and their annotated locations for XP_008768712.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:433560
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    5. XM_008770492.2XP_008768714.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X6

      See identical proteins and their annotated locations for XP_008768714.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:422549
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    6. XM_008770493.2XP_008768715.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X7

      See identical proteins and their annotated locations for XP_008768715.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:418545
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    7. XM_008770494.2XP_008768716.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X10

      See identical proteins and their annotated locations for XP_008768716.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:407534
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    8. XM_008770489.2XP_008768711.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3

      See identical proteins and their annotated locations for XP_008768711.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:435562
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    9. XM_008770491.2XP_008768713.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5

      See identical proteins and their annotated locations for XP_008768713.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:424551
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    10. XM_008770498.2XP_008768720.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X14

      See identical proteins and their annotated locations for XP_008768720.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:384511
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    11. XM_017599576.1XP_017455065.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X9

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:412539
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    12. XM_008770495.2XP_008768717.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X11

      See identical proteins and their annotated locations for XP_008768717.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:401528
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    13. XM_008770496.2XP_008768718.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X12

      See identical proteins and their annotated locations for XP_008768718.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:397524
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    14. XM_017599577.1XP_017455066.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X15

    15. XM_008770497.2XP_008768719.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X13

      See identical proteins and their annotated locations for XP_008768719.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:386513
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    16. XM_008770499.2XP_008768721.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X16

      See identical proteins and their annotated locations for XP_008768721.1

      UniProtKB/Swiss-Prot
      P11730
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:363490
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
    17. XM_017599575.1XP_017455064.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X8

    RNA

    1. XR_001841253.1 RNA Sequence

      Related
      ENSRNOT00000065644.4

    Alternate Rn_Celera

    Genomic

    1. AC_000083.1 Alternate Rn_Celera

      Range
      1033077..1088815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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