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    Fgf7 fibroblast growth factor 7 [ Mus musculus (house mouse) ]

    Gene ID: 14178, updated on 16-May-2017
    Official Symbol
    Fgf7provided by MGI
    Official Full Name
    fibroblast growth factor 7provided by MGI
    Primary source
    MGI:MGI:95521
    See related
    Ensembl:ENSMUSG00000027208 Vega:OTTMUSG00000015341
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kgf
    Orthologs
    Location:
    2; 2 F1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (126034658..126091185)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (125860394..125916921)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene family with sequence similarity 227, member B Neighboring gene DTW domain containing 1 Neighboring gene ATPase, class I, type 8B, member 4 Neighboring gene Brca1 associated protein 1 pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chemoattractant activity ISO
    Inferred from Sequence Orthology
    more info
     
    fibroblast growth factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    growth factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    heparin binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    type 2 fibroblast growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    actin cytoskeleton reorganization ISO
    Inferred from Sequence Orthology
    more info
     
    branching involved in salivary gland morphogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fibroblast growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    hair follicle morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lung development ISO
    Inferred from Sequence Orthology
    more info
     
    mesenchymal cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    ovarian follicle development ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylcholine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell division IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of epithelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of epithelial cell proliferation involved in lung morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of keratinocyte migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of keratinocyte proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-tyrosine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    secretion by lung epithelial cell involved in lung growth ISO
    Inferred from Sequence Orthology
    more info
     
    surfactant homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    wound healing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    fibroblast growth factor 7
    Names
    FGF-7
    HBGF-7
    Keratinocyte growth factor
    heparin-binding growth factor 7

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008008.4NP_032034.1  fibroblast growth factor 7 precursor

      See identical proteins and their annotated locations for NP_032034.1

      Status: VALIDATED

      Source sequence(s)
      AK037172, AL845292
      Consensus CDS
      CCDS16681.1
      UniProtKB/Swiss-Prot
      P36363
      UniProtKB/TrEMBL
      Q544I6
      Related
      ENSMUSP00000069681.7, OTTMUSP00000016341, ENSMUST00000064794.13, OTTMUST00000036358
      Conserved Domains (1) summary
      smart00442
      Location:63191
      FGF; Acidic and basic fibroblast growth factor family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      126034658..126091185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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