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    Mcm4 minichromosome maintenance complex component 4 [ Mus musculus (house mouse) ]

    Gene ID: 17217, updated on 8-Apr-2018
    Official Symbol
    Mcm4provided by MGI
    Official Full Name
    minichromosome maintenance complex component 4provided by MGI
    Primary source
    MGI:MGI:103199
    See related
    Ensembl:ENSMUSG00000022673
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    19G; Cdc21; Mcmd4; mcdc21; AI325074; AU045576; mKIAA4003
    Expression
    Broad expression in liver E14 (RPKM 36.5), liver E14.5 (RPKM 34.4) and 21 other tissues See more
    Orthologs
    Location:
    16 A2; 16 10.09 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (15623897..15637400, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (15623990..15637493, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 variant 2 Neighboring gene predicted gene 7748 Neighboring gene protein kinase, DNA activated, catalytic polypeptide Neighboring gene mitotic spindle organizing protein 2

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • KIAA4003

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ATP-dependent DNA helicase activity ISO
    Inferred from Sequence Orthology
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    single-stranded DNA binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
     
    DNA unwinding involved in DNA replication IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    MCM complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    DNA replication licensing factor MCM4
    Names
    CDC21 homolog
    P1-CDC21
    mini chromosome maintenance deficient 4 homolog
    minichromosome maintenance deficient 4 homolog
    NP_032591.3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008565.3NP_032591.3  DNA replication licensing factor MCM4

      See identical proteins and their annotated locations for NP_032591.3

      Status: VALIDATED

      Source sequence(s)
      AK036653, AK141644, AK151499
      Consensus CDS
      CCDS27977.1
      UniProtKB/Swiss-Prot
      P49717
      UniProtKB/TrEMBL
      Q3UA65, Q542F4
      Related
      ENSMUSP00000023353.3, ENSMUST00000023353.3
      Conserved Domains (3) summary
      smart00350
      Location:266769
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:165286
      MCM_N; MCM N-terminal domain
      cl21455
      Location:504643
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      15623897..15637400 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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